The relationship between the distribution of red blood cell distribution width and NYHA classification and the effect of short-term prognosis in patients with chronic heart failure
HUANG Si-shi
Department of the First Internal Medicine,Yangchun People′s Hospital of Guangdong Province,Yangchun529600,China
Abstract Objective To study the relationship between the distribution of red blood cell distribution width(RDW)and NYHA classification and the effect of short-term prognosis in patients with CHF.Methods A total of 193 patients who were hospitalized in our hospital and diagnozed as CHF from June 2013 to June 2015.According to the NYHA divided into A group(55 cases，gradeⅠ),B group(42 cases，gradeⅡ),C group(48 cases，gradeⅢ),D group(48 cases，gradeⅣ).Cox regression analysis was used to analyze the risk factors of death in patients with CHF.Results Hemoglobin(Hb) and red blood cell(RBC)decreased with the increase of NYHA grade;Hb and RBC of group A,group B,group C,group D were decreased,the difference was statistically significant(F1=4.044,F2=2.906,P＜0.05);LgNT-proBNP of group A,group B, group C,group D were increased,the difference was statistically significant(F=3.492,P＜0.01);Cox forward stepwise regression analysis showed that RDW,Hb,N-terminal B-type natriuretic peptide(LgNT-proBNP)and age were independent predictors of poor prognosis in patients with CHF(HR=1.892,3.924,0.925,1.003,P＜0.05).Conclusion Compared with age and Hb factor,RDW level has a better independent predictive value for the NYHA classification of CHF patients.
HUANG Si-shi. The relationship between the distribution of red blood cell distribution width and NYHA classification and the effect of short-term prognosis in patients with chronic heart failure[J]. 中国当代医药, 2017, 24(7): 56-59.
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