Abstract ObjectiveTo explore the treatment methods of health education with Liraglutide monotherapy treatment of newly diagnosed overweight patients with type 2 diabetes,which can further provide the theoretical basis and reference for clinical application.Methods30 cases of overweight patients with type 2 diabetes from June 2014 to May 2016 in our hospital were selected as the research object,they were divided into education united group(n=15)and Liraglutide group (n=15)using the random number table method.Liraglutide group was given a separate Liraglutide monotherapy, subcutaneous injection,18 mg/d,injection 12 weeks in a row,education united group was given Liraglutide monotherapy and health education.Then the difference of blood pressure,body weight,body mass index (BMI),low density lipoprotein cholesterol(LDL-C),triglyceride(TG),total cholesterol(TC),fasting C peptide(FC-P),HOMA-IR(CP),HOMA IR islet(CP), glycosylated hemoglobin(HbA1c),postprandial 2 h blood glucose(2 h PG),fasting plasma glucose(FPG),and other indicators was compared between the two groups.ResultsThe FPG,2 h PG,HbA1c,weight,BMI,SB,FC-P,HOMA islet,HOMA-IR, TC,TG and LDL-C were significantly lower compard with before treatment,and education united group had more significantly reduce compared with Liraglutide group,the difference value of before and after treatment in the two groups had statistically significant difference(P<0.05).ConclusionThe combination with health education and Liraglutide is a kind of effective treatment to overweight type 2 diabetes patients,and superior than the Liraglutide monotherapy,because it can effectively control overweight type 2 diabetes patients with body weight,lower blood pressure,FPG,2 h PG,and it plays a role in lipid regulation as well.
WANG Hai-yan,LIU Hui-xia. Clinical analysis of health education with Liraglutide monotherapy treatment of newly diagnosed overweight patients with type 2 diabetes[J]. 中国当代医药, 2017, 24(11): 51-54.
