Abstract ObjectiveTo study the effect of gestational diabetes on fetal growth and development.M ethodsFrom July to December 2016,the pregnantwomen with gestational diabetesmellitus(estational diabetesmellitus group,50 cases)and normal pregnantwomen (normal pregnantwomen group,50 cases)were selected as the subjects.All pregnantwomen
received:test of prenatal blood glucose and ultrasonic.The FPG,glucose level of OGTT 1 h,glucose level of OGTT 2 h and HbA1c were obtained by 75 g oral glucose tolerance test.The testing results of pregnantwomen were compared between the two groups,the fetal abdominal circumference measured by ultrasound at 32 weeks was recorded and the fetal growth ratewere calculated.The correlation between the HbA1c and the growth speed of the fetuseswas analyzed.At the same time,the birth weight and Apgar scores of neonates after delivery of pregnantwomen were compared between the two groups.ResultsThe test value of FPG,OGTT 1 h PG,OGTT 2 h PG and HbA1c,the fetal abdominal circumference at 32 weeks and the growth speed in pregnant women with gestational diabetes mellitus were significantly higher than those in normal pregnantwomen group,the differenceswere statistically significant(P<0.05).Pearson correlation analysis showed that,there was a significant positive correlation between the HbA1c level and the growth speed of the fetuses of the two groups(r=0.694,P<0.05).At the same time,the neonatal Apgar score of the pregnantwomen with gestational diabetesmellitus after delivery was significantly lower than the normal group,and themacrosomia fetuses birth rate was significantly higher than that of normal pregnantwomen,the differenceswere statistically significant(P<0.05).ConclusionThe occurrence of gestational diabetesmellitus can accelerate the growth of the fetuses,the increase in the proportion of themacrosomia fetuses after delivery andmay cause adverse pregnancy outcome.
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