空腹三酰甘油与不同时间动脉粥样硬化指数的相关性

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Abstract Objective To investigate the correlation between fasting triacylglycerol (TAG) and atherosclerosis index (AI)at different times.Methods A total of 24 outpatients with type 2 diabetes mellitus(T2DM)in Traditional Chinese Medicine Hospital of Urumqi from January 2019 to December 2019 were selected. The patients were divided into fasting TAG increased group (n=10, fasting TAG＞1.8 mmol/L) and fasting TAG normal group (n=14, fasting TAG≤1.8 mmol/L), according to fasting TAG level. The general data, incidence of atherosclerosis, peak time of TAG, lipids metabolism at fasting and 2, 4 and 6 hours after meal (TAG, total cholesterol [TC], low density lipoprotein [LDL-C] and high density lipoprotein [HDL-C]), blood glucose, insulin, glycosylated hemoglobin (HbA1c), C-Peptide, tumor necrosis factor-α (TNF-α)and malondialdehyde (MDA) were compared in the two group to analyze the correlation between TAG and AI. Results The peak time of both group was 4 hours after meal. The TAG and TC of fasting and postprandial 2, 4 and 6 hours in the fasting TAG increased group were higher than fasting TAG normal group with statistically significant difference (P＜0.05). AI of postprandial 2, 4 and 6 hours in fasting TAG increased group was higher than fasting TAG normal group(P＜0.05). Fasting TAG was positively correlated with fasting AI (r=0.552, P＜0.05). Postprandial 2 hours TAG was positively associated with postprandial 2 hours AI (r=0.868, P＜0.05). Postprandial 4 hours TAG was positively associated with postprandial 4 hours AI (r=0.710, P＜0.05). Postprandial positive correlation of 6 hours TAG with postprandial 6 hours AI (r=0.767, P＜0.05). Conclusion There is a positive correlation between TAG and AI in T2DM patients. Therefore, early detection of fasting and postprandial TAG levels in T2DM patients can provide data support for clinical evaluation of dyslipidemia and judgment of atherosclerosisThere is a positive correlation between TAG and AI in T2DM patients. Therefore, early detection of fasting and postprandial TAG levels in T2DM patients can provide data support for clinical evaluation of dyslipidemia and judgment of atherosclerosis.

Key words： Fasting Triglycerides Type 2 diabetes mellitus Standard fat meal Lipid metabolism Peak time;Atherosclerosis index

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	WANG Di

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WANG Di. Correlation between fasting triacylglycerol and atherosclerosis index at different times[J]. 中国当代医药, 2021, 28(28): 79-84.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I28/79

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