动脉内机械取栓治疗缺血性脑卒中的效果及其影响因素分析

Abstract
Figure/Table
References (16)
Related Citation (15)

Download: PDF (0 KB) HTML (33 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the effect and influencing factors of intra - arterial mechanical thrombectomy in the treatment of ischemic stroke. Methods Clinical data of 113 patients with ischemic stroke admitted to General Hospital of Pingxiang Mining Group Co., Ltd. from January 2018 to March 2020 were retrospectively analyzed and divided into group A (53 cases) and group B (60 cases) according to treatment methods. Patients in group A were treated with intra-arterial thrombolysis, and patients in group B were treated with intra-arterial mechanical thrombectomy. Group B patients were then divided into good prognosis group (40 cases) and poor prognosis group (20 cases) according to prognosis. The hemodynamic indexes of group A and group B before and 14 days after surgery were compared. The basic clinical data of patients with good prognosis and patients with poor prognosis were compared, and the influencing factors of prognosis were analyzed. Results 14 days after surgery, the maximum peak flow velocity (VS) in group A and B was higher than that before surgery, and group B was higher than group A, while the vascular resistance index (RI) and vascular pulse index (PI) were lower than that before surgery, and group B was lower than group A, the differences were statistically significant (P<0.05). Univariate analysis showed that the proportion of males, the proportion of recanalization, and the preoperative Alberta stroke program early CT (ASPECT) score in the good prognosis group were higher than those in the poor prognosis group, and the time from admission to recanalization was shorter than that in the poor prognosis group. The proportion of posterior circulatory occlusion site, National institutes of health stroke scale (NIHSS)score 24 h after surgery and intracranial hemorrhage rate were lower than those in the poor prognosis group, the differences were statistically significant (P<0.05). Multivariate Losgistic regression analysis showed that the occlusion of the posterior circulation, the time from admission to recanalization≥140 min, the NIHSS score≥10 points at 24 h after surgery, and the occurrence of intracranial hemorrhage at 24 h after surgery were all treated by intraarterial mechanical thrombectomy for ischemic Risk factors for poor prognosis after stroke (P<0.05). Conclusion Intraarterial mechanical thrombectomy can improve the hemodynamics of patients with ischemic stroke and effectively open blood vessels. At the same time, intervention should be aimed at the risk factors of poor prognosis to improve the prognosis of patients.

Key words： Mechanical intra-arterial embolectomy Ischemic stroke Prognosis Influencing factors

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	HU Shan
	ZHENG Chao
	HE Huan

Cite this article:

HU Shan,ZHENG Chao,HE Huan. Effect and influencing factors of intra-arterial mechanical thrombectomy in the treatment of ischemic stroke[J]. 中国当代医药, 2021, 28(21): 9-12.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I21/9

[1]	王娟.缺血性脑卒中临床治疗方法的研究进展[J].现代诊断与治疗，2018，29（16）：20-22.
[2]	刘广会.缺血性和出血性脑卒中危险因素分析[J].中国卫生工程学，2018，17（2）：260-262.
[3]	宋云骏，于海侠，关亚男，等.急性缺血性脑卒中静脉溶栓治疗研究进展[J].河北医学，2018，24（2）：350-352.
[4]	李青松，陈珑，刘一之，等.动脉内机械取栓治疗急性后循环缺血性脑卒中临床效果及预后影响因素[J].中国介入影像与治疗学，2019，16（6）：333-337.
[5]	黄浩，骆翔.急性缺血性脑卒中机械取栓治疗研究进展[J].神经损伤与功能重建，2018，13（12）：637-640.
[6]	中华医学会神经病学分会，中华医学会神经病学分会脑血管病学组.中国急性缺血性脑卒中诊治指南2018[J].中华神经科杂志，2018，51（9）：666-682.
[7]	李雪微，张雯，李笑笑，等.急性缺血性卒中病人mRS 评分与中医证型的相关性研究[J].中西医结合心脑血管病杂志，2018，16（19）：125-128.
[8]	金灿，王苇.ASPECT 评分的临床应用进展[J].国际医学放射学杂志，2015，38（5）：418-422.
[9]	张刚，张劲松，蒋雷，等.D-二聚体与脑梗死发病时间及溶栓前后NIHSS 评分的关系[J].南京医科大学学报（自然科学版），2017，37（11）：1448-1450.
[10]	李继坤，刘祺，田卫东，等.急性缺血性脑卒中血管内治疗的临床应用[J].临床神经外科杂志，2018，15（4）：275-281.
[11]	杨勇涛，鲍娟，曹毅，等.急性缺血性脑卒中血管内治疗21 例临床分析[J].国际神经病学神经外科学杂志，2020，47（2）：15-20.
[12]	魏鹏，唐景峰.急性缺血性脑卒中机械取栓临床治疗新进展[J].临床医药文献电子杂志，2019，6（35）：189-191.
[13]	任海兵，颜静，赵晓晖，等.急性前循环大血管闭塞性脑卒中机械取栓术后颅内出血的影响因素分析[J].中华神经医学杂志，2020，19（9）：890-896.
[14]	刘春梅，周俊山，张羽乔，等.静脉溶栓与桥接治疗颅内大动脉闭塞性脑梗死的临床疗效与安全性[J].临床神经病学杂志，2018，31（6）：15-19.
[15]	殷涛，韩靖，赵腾跃.介入治疗血管内溶栓联合机械取栓对急性缺血性脑卒中患者脑血管血流状态及预后的影响[J].中国医刊2020，55（7）：757-761.
[16]	吕华东，马可，蓝瑞芳，等.经以机械取栓为主的动脉内多模式治疗的大动脉闭塞性脑梗死患者短期预后的影响因素研究[J].实用心脑肺血管病杂志，2018，26（1）：38-41.