神经内镜微创术对高血压性脑出血患者血肿清除率及神经功能的影响

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Abstract Objective To explore the effect of neuroendoscopic microtrauma (NM) on hematoma clearance rate (HCR)and neurological function (NF) in patients with hypertensive cerebral hemorrhage (HCH). Methods A total of 40 patients with HCH admitted to Wafangdian Central Hospital from March 2018 to February 2020 were retrospectively collected and divided into the control group (n=17) and the observation group (n=23) according to different surgical treatments. The control group were treated with craniotomy minimally invasive hematoma removal and the observation group were treated with NM. HCR, stress response, score of NF, and the incidence of complications were compared between the two groups. Results HCR in the observation group was higher than in the control group, and the total incidence of complications was lower than that of the control group, the differences were statistically significant (P<0.05). There were no statistical significance in the preoperative NF score or oxidative stress between the two groups (P>0.05). The levels of endothelin (ET) and cortisol (Cor) 24 hours after operation in the observation group were lower than those in the control group, the differences were statistically significant (P<0.05). Six months after operation, the Chinese stroke scale(CSS) score of the observation group was lower than that of the control group, the difference was statistically significant(P<0.05). The total incidence of complications in the observation group was lower than that in the control group, the difference was statistically significant (P<0.05). Conclusion NM for patients with HCH can improve HCR, reduce stress response and improve NF, with high safety.

Key words： Hypertensive cerebral hemorrhage Neuroendoscopic microtrauma Craniotomy minimally invasive hematoma removal Hematoma clearance rate Stress response Neurological function

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	Articles by authors
	WANG Dan
	JIAO Jun-zheng
	WANG Sheng-da
	ZHOU Chao
	YANG Guang-yu

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WANG Dan,JIAO Jun-zheng,WANG Sheng-da, et al. Effect of neuroendoscopic microtrauma on hematoma clearance rate and neurological function in patients with hypertensive cerebral hemorrhage[J]. 中国当代医药, 2021, 28(16): 102-104.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I16/102

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