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| Effect of Budesonide Fomoterol combined with pulmonary rehabilitation training on pulmonary function and improvement of quality of life in patients with moderate-severe chronic obstructive pulmonary disease in stable phase |
| ZHU Cai-liang |
| Department of Respiratory Medicine,the Second People′s Hospital of Nankang District in Ganzhou City,Jiangxi Province,Ganzhou 341411, China |
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Abstract Objective To investigate the effect of Budesonide Formoterol combined with pulmonary rehabilitation training on lung function and quality of life in moderate to severe chronic obstructive pulmonary disease (COPD) patients at stable stage.Methods A total of 86 patients with moderate and severe COPD who were treated in the Second People′s Hospital of Nankang District in Ganzhou City from July 2017 to December 2019 were selected as the research subjects.According to random number table method,they were divided into control group(43 cases)and observation group(43 cases).The control group was treated with Budesonide Formoterol, and the observation group was treated with pulmonary rehabilitation training on the basis of the control group.Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), 6-min walking distance, quality of life score and acute attack rate were compared between the two groups.Results After treatment, the FVC and FEV1 of the observation group were (2.89±0.41) and (2.03±0.35) L, which were higher than those of the control group (2.57±0.38) and (1.81±0.31) L, the differences were statistically significant (P＜0.05).After treatment, the 6 min walking distance of the observation group was (364.78±25.65) m, longer than that of the control group of (324.14±23.59) m, and the difference was statistically significant (P＜0.05).After treatment, COPD assessment test (CAT) score and modified British medical research council dyspnea index (mMRC) score in the observation group were (14.39±2.42) and (1.59±0.22)points, lower than those in the control group of (18.93±2.56) and (1.81±0.25) points, the differences were statistically significant (P＜0.05).The acute attack rate of the observation group was 4.65%, lower than that of the control group (18.60%), the difference was statistically significant (P＜0.05).Conclusion Budesonide Formoterol combined with pulmonary rehabilitation training can enhance lung function,reduce the number of acute attacks and improve the quality of life in patients with moderate to severe COPD.
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| Cite this article: |
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ZHU Cai-liang. Effect of Budesonide Fomoterol combined with pulmonary rehabilitation training on pulmonary function and improvement of quality of life in patients with moderate-severe chronic obstructive pulmonary disease in stable phase[J]. 中国当代医药, 2021, 28(10): 67-70.
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| URL: |
| http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I10/67 |
| [1] |
姚香萍.布地奈德联合异丙托溴铵治疗慢性阻塞性肺疾病的临床研究[J].现代药物与临床，2019，34（10）：2985-2989.
|
| [2] |
庄英鸿，尚东，巫瑞.噻托溴铵联合布地奈德福莫特罗吸入剂治疗稳定期慢性阻塞性肺疾病的临床疗效研究[J].药物评价研究，2017，40（11）：1626-1630.
|
| [3] |
区健民，祝小林，张强，等.布地奈德福莫特罗粉吸入剂与氨茶碱片治疗缓解期慢性阻塞性肺疾病的疗效对比[J].广西医科大学学报，2017，34（4）：575-578.
|
| [4] |
秦芳，李红，张贤莉.高压氧联合布地奈德福莫特罗对慢性阻塞性肺病稳定期患者血清TGF-β1 和sTREM-1 的影响[J].中华航海医学与高气压医学杂志，2019，26（5）：465-467.
|
| [5] |
李新鹏.布地奈德福莫特罗联合呼吸康复训练治疗慢性阻塞性肺疾病的疗效观察[J].中国临床医生杂志，2017，45（5）：41-43.
|
| [6] |
中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺疾病诊治指南（2013年修订版）[J].中国医学前沿杂志（电子版），2014，（2）：67-79，80.
|
| [7] |
王运.布地奈德联合福莫特罗雾化吸入治疗慢性阻塞性肺疾病的效果及其对患者肺功能和炎性递质的影响[J].新乡医学院学报，2017，34（10）：932-935.
|
| [8] |
喻敏.金水宝胶囊联合布地奈德福莫特罗治疗慢性阻塞性肺疾病稳定期的临床研究[J].现代药物与临床，2019，34（9）：2645-2648.
|
| [9] |
韩娟，颜浩，徐淑晖，等.噻托溴铵联合布地奈德福莫特罗对慢性阻塞性肺疾病的疗效及对TGF-β、TIMP-1、IL-6水平的影响[J].现代生物医学进展，2018，18（13）：2531-2534，2544.
|
| [10] |
夏文娟，王学中.布地奈德福莫特罗联合噻托溴铵对慢性阻塞性肺疾病急性加重期的临床疗效[J].安徽医学，2017，38（12）：1572-1574.
|
| [11] |
王新梅，栾念旭，靳岱红.噻托溴铵联合布地奈德福莫特罗治疗稳定期COPD 疗效及对细胞免疫功能的影响[J].中国医师杂志，2019，21（8）：1254-1256.
|
| [12] |
刘文华.噻托溴铵联合福莫特罗吸入治疗慢性阻塞性肺疾病的临床效果[J].中国当代医药，2020，27（9）：37-39，43.
|
| [13] |
林明江，汤秀珍，梁锦泉.布地奈德福莫特罗吸入剂联合肺康复训练治疗中重度COPD 疗效研究[J].中国医药科学，2018，8（4）：30-32，36.
|
| [14] |
楼亚波，群智，盛美玲，等.心肺康复训练对COPD 稳定期患者肺功能及生活质量的影响[J].中国慢性病预防与控制，2018，26（5）：361-363.
|
| [15] |
计樱莹，郝建凤，苏敏.音乐治疗辅助肺康复训练对COPD患者康复治疗的研究[J].中国康复，2019，34（3）：150-154.
|
| [16] |
刘云霞，刘志华，任翠萍，等.吸入舒利迭联合有氧运动及心肺康复训练对COPD 患者心肺功能、BODE 指数及运动耐量的影响[J].解放军预防医学杂志，2019，37（8）：130-131，134.
|
| [17] |
桑义民，宁瑞男，陈雪.百令胶囊联合呼吸康复训练治疗慢阻肺的疗效及对患者血气指标、肺功能的影响[J].中国现代医生，2019，57（10）：26-28.
|
|
|
|
