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Application of repeated transcranial magnetic stimulation in long-term hospitalized patients with schizophrenia |
QIN Yan-yan LI Mei-juan FU Ping-ping ZHANG Yu-e |
Department of Rehabilitation,Huizhou No.2 People′s Hospital,Guangdong Province,Huizhou 516001,China |
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Abstract Objective To explore the clinical effect of repeated transcranialmagnetic stimulation(rTMS)in long-term hospitalized patients with schizophrenia.Methods Fifty patients with schizophrenia treated in the department of psychiatry in our hospital from February to August 2017 were selected as the research subjects,and were divided into experimental group(n=25)and control group(n=25)according to the order of patient visits.Patients in the control group were given sham stimulation,and patients in the experimental group were provided with rTMS.The scores of the positive and negative symptoms scale(PANSS)before and after 4-and 8-week treatments and 6-month follow-up were compared.Themental nursing observation rating scale(NORS)scores and personal and social performance scale(PSP)before and after treatment were compared.Results The positive symptoms and general mental scores of the experimental group at 4-and 8-week treatments and 6-month follow-up were lower than those of the control group,the total scores of PANSS after 8-week treatment and 6-month follow-up in the experimental group were lower than those of the control group(P<0.05).The self-care ability score of the experimental group after treatmentwas higher than that of the control group,and the PSP scores at 4-and 8-week treatment and 6-month follow-up were higher than those of the control group,the scores of recreational activity,environmental adaptation and mental symptoms,and total score were lower than those in the control group(P<0.05).Conclusion rTMShas a positive effect on the social function and quality of life in long-term hospitalized patients with schizophrenia,and can effectively improve the social function and quality of life.
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