孟鲁司特钠结合雾化吸入布地奈德治疗支气管哮喘患儿的效果

Abstract
Figure/Table
References (22)
Related Citation (15)

Download: PDF (0 KB) HTML (37 KB)
Export: BibTeX | EndNote (RIS)

Abstract

Objective To explore the effect of Montelukast Sodium combined with Budesonide aerosol inhalation in the treatment of children with asthma.Methods A total of 86 cases of children with asthma treated in our hospital from August 2017 to December 2019 were selected as the research objects.The selected patients were divided into the observation group (n=43) and the control group (n=43) according to random number table method.The children in the control group were treated with Budesonide aerosol inhalation, and the children in the observation group were treated with Montelukast Sodium combined with Budesonide aerosol inhalation, the changes of clinical treatment effect, peak expiratory flow (PEF) and forced expiratory volume in the first second (FEV1) of the two groups were observed.Results After treatment, the FEV1 and PEF of the two groups of children were higher than those before treatment, the differences were statistically significant (P<0.05).The FEV1 and PEF in the observation group after treatment were higher than those in the control group, the differences were statistically significant (P<0.05).Through treatment, the total effective rate of children in the observation group was 95.35%, higher than the control group (81.40%), the difference was statistically significant (P<0.05).The total incidence of adverse reactions in the observation group was 2.33%, lower than the control group (13.95%), the difference was statistically significant (P<0.05).Conclusion Montelukast Sodium combined with Budesonide aerosol inhalation in the treatment of bronchial asthma has a significant effect, can significantly improve the lung function of children, clinical application value is high.

Key words： Sodium rooster Aerosol inhalation Budesonide Bronchial asthma Pulmonary function Effect

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	MA Zhu

Cite this article:

MA Zhu. Effect of Montelukast Sodium combined with Budesonide aerosol inhalation in the treatment of children with asthma[J]. 中国当代医药, 2020, 27(20): 139-141转145.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I20/139

[1]	周海霞，常蕊静，姜鹏，等.支气管哮喘过敏原血清特异性免疫球蛋白E 及总免疫球蛋白E、嗜酸性粒细胞阳离子蛋白的测定及分析[J].中华肺部疾病杂志，2017，10（3）：300-303.
[2]	孙丽媛，韩琴，任宝香.呼出气一氧化氮对支气管哮喘的诊断价值[J].吉林医学，2016，37（9）：2129-2130.
[3]	刘洁露，于化鹏，谭晓媚，等.支气管激发试验与舒张试验对支气管哮喘患者呼出气一氧化氮测定值的影响和意义[J].中华结核和呼吸杂志，2016，39（3）：189-192.
[4]	林武洲.支气管舒张试验的舒张时间对支气管哮喘的诊断价值[J].临床肺科杂志，2012，17（7）：1306-1307.
[5]	玄春实，王利菊，张萍，等.从过敏原检测与支气管舒张试验相关性看COPD与支气管哮喘的鉴别诊断[J].2012，19（33）：21-23.
[6]	谭晓媚，于化鹏，刘洁露，等.呼出气一氧化氮测定在支气管哮喘诊断中的应用[J].山东医药，2016，56（23）：65-67.
[7]	柏丹丹.普米克气雾剂联合孟鲁司特治疗小儿哮喘的临床效果分析[J].临床医药文献电子杂志，2017，25（55）：10 812.
[8]	刘志伟，梁宇，杨继俊，等.孟鲁司特钠联合布地奈德治疗支气管哮喘临床疗效观察[J].北方药学，2017，14（3）：153-154.
[9]	白素娟.孟鲁司特钠联合布地奈德治疗支气管哮喘的疗效观察[J].医学理论与实践，2017，30（15）：2242-2243.
[10]	林振涛.孟鲁司特钠联合布地奈德治疗支气管哮喘患者的临床效果[J].医疗装备，2019，32（22）：94-95.
[11]	吴晶.孟鲁司特钠联合布地奈德治疗支气管哮喘的临床效果评价[J].中国医药指南，2018，16（4）：131-132.
[12]	温琼娜，陈俊先，许志成，等.孟鲁司特钠片联合布地奈德对支气管哮喘患者的疗效及免疫功能和肺功能的影响[J].中国医学创新，2019，16（10）：41-44.
[13]	高伟霞，秦小菀，张靖.孟鲁司特钠颗粒联合吸入用布地奈德混悬液治疗小儿支气管哮喘的疗效及其对血清抗凝血酶m、CD5 抗原样蛋白和补体3 水平的影响[J].新乡医学院学报，2019，36（4）：368-372.
[14]	王静，佟金平，李剑，等.孟鲁司特钠联合布地奈德对支气管哮喘患者肺功能、生活质量的影响[J].中国现代药物应用，2018，12（6）：6-8.
[15]	王学锷.孟鲁司特钠联合布地奈德治疗支气管哮喘临床效果评价[J].医学信息，2017，30（12）：85-86.
[16]	郑怀玉.孟鲁司特钠与布地奈德应用于支气管哮喘治疗的效果研究[J].海峡药学，2017，29（12）：179-180.
[17]	吴海丽，李贤斌.气雾型布地奈德联合孟鲁司特钠治疗小儿咳嗽变异性哮喘疗效及对肺功能和血清炎症因子的影响[J].海南医学院学报，2016，22（5）：467-470.
[21]	杨敏，李林瑞，孟燕妮，等.布地奈德辅助治疗小儿支气管哮喘对T淋巴细胞亚群及相关细胞因子的影响[J].疑难病杂志，2018，17（3）：255-258.
[18]	OS Khukhlina，AA Antoniv，OY Mandryk，et al.Clinical and pathogenetic features of nonalcoholic steatohepatitis for comorbidity with bronchial asthma on the background of obesity[J].Wiad Lek，2018，71（2 pt 1）：376-379.
[19]	Takizawa T.Transitional care of adolescents with bronchial asthma [J].Jpn J Pediatric Allergy Clin Irnmunol，2018，32（1）：74-81.
[20]	Susmit S.Diggikar，Tanaji D.Nandgude，Sushilkumar S.Poddar.Formulation of Modified Release Pellets of Montelukast Sodium[J].Res J Pharm Technol，2018，11（1）：31-37.
[22]	Mosavi SH，Esmaeili AK，Azhdari S.Evaluating Economic Effects of Exchange Rate Depreciation on the Rice Market in Iran[J].JIA，2018，16（4）：705-715.