Abstract Objective To investigate the timing of prevention and treatment of postpartum hemorrhage of uterine contractions (PPH) by Carbendazim Aminobutanol Injection, and then to guide the prevention and treatment of PPH.Methods A total of 180 cases of PPH tendency treated in our hospital from August 2017 to August 2019 were selected as the study subjects, and they were divided into group A, group B and group C according to the random digital table method, 60 cases in each group.group A:after the delivery of the fetus, the uterine muscle was injected with 250 μg of Carbendazim Injection and intravenous drip of 20 U Oxytocin.Group B:after deliver, drop 20 U Oxytocin, if the bleeding amount reached 400 ml, the uterine muscle was injected with 250 μg of Carbendazim Triol Injection.Group C:after delivery of the fetus, the uterine muscle was injected with 20 U Oxytocin and intravenous drip of 20 U Oxytocin, when the bleeding amount reached 800 ml, the uterine muscle was injected with 250 μg of Carbendazim Triol Injection.The incidence of 24 h postpartum hemorrhage, postpartum hemorrhage, prenatal and postnatal hemoglobin and adverse reactions during medication in the two groups were evaluated.Results The amount of postpartum hemorrhage in group A was less than that in group B and group C, and that in group B was less than that in group C,with statistical differences (P<0.05);the incidence of postpartum hemorrhage in group A was lower than that in group B and group C, with statistical difference (P<0.05).There was no significant difference in the incidence of postpartum hemorrhage in group C and group B (P>0.05).The hemoglobin level of the three groups at 24 hours after delivery was lower than that before delivery, with statistical differences (P<0.05), the level of 24 h hematocrit in group A was higher than that in group B and group C, with statistical difference (P<0.05).There was no significant difference in the incidence of adverse reactions among the three groups (P>0.05).Conclusion Carbendazim Tributanol Injection can prevent and treat the PPH better, using Carbendazim Tributanol Injection as early as possible to reduce the amount of postpartum hemorrhage, reduce the incidence of postpartum hemorrhage and ensure the safety of parturient.
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