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| Changes and significance of levels of procalcitonin, C-reactive protein and prealbumin in children with bacterial infection |
| LEI Yuan1 LIU Jing2 YANG Bo1▲ |
1. Department of Pediatrics, Changsha Fourth Hospital, Hu′nan Province, Changsha 410006, China；
2. Changsha Health Vocational College, Hu′nan Province, Changsha 410600, China |
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Abstract Objective To analyze the changes and significance of procalcitonin (PCT), C-reactive protein (CRP) and prealbumin (PA) levels in children with bacterial infection. Methods A total of 120 children with infectious diseases treated in Changsha Fourth Hospital from March 2016 to March 2019 were analyzed retrospectively, included 60 cases in the bacterial infection group and 60 cases in the viral infection group. Meanwhile, 60 children who underwent physical examination in Changsha Fourth Hospital were selected as the control group. To test the levels of PCT, CRP and PA in the three groups. Results The positive rates of PCT, CRP and PA levels in the bacterial infection group and their combined detection were higher than those in the viral infection group and the control group, the differences were statistically significant (P＜0.05). The positive rate of all indicators in the viral infection group was compared that in the control group, the difference was not statistically significant (P＞0.05). Serum PCT and CRP levels in the bacterial infection group were higher than those in the viral infection group and the control group (P＜0.05). PA level was lower than that of the viral infection group and control group, the difference was statistically significant (P＜0.05). However,the levels of PCT, CRP and PA in the viral infection group were not significantly different from those in the control group (P ＞0.05). Conclusion The detection of PCT, CRP and PA levels have certain clinical value in identifying whether infectious diseases in children are bacterial or viral infections.
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