丙泊酚静脉麻醉在急性重型颅脑损伤手术患者中的应用效果

Abstract
Figure/Table
References (17)
Related Citation (15)

Download: PDF (0 KB) HTML (35 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the application effect of Propofol intravenous anesthesia in patients with acute severe craniocerebral injury surgery.Methods From June 2014 to June 2017,118 patients with acute severe craniocerebral injury were selected and they were randomly divided into the control group (59 cases)and the observation group(59 cases).The control group was anesthetized with Etomidate,while the observation group was anesthetized with Propofol.The intracranial pressure(ICP),cerebral oxygen partial pressure(PbrO2),cellular inflammatory factor level and recovery time were compared between the two groups.Results The ICP of T4and T5in the observation group was lower than that of the control group,the PbrO2of T4and T5in the observation group was higher than that of the control group,and the differences were statistically significant(P＜0.05).The IL-1,IL-6,TNF-α and S100β level in the observation group were lower than those of the control group at T5,and the differences were statistically significant(P＜0.05).The recovery time for the first time of the observation group was shorter than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Propofol intravenous anesthesia applied in patients with acute severe craniocerebral injury surgery protect brain function,reduce inflammation and shorten postoperative recovery time in patients.

Key words： Acute severe craniocerebral injury Surgery Propofol Intravenous anesthesia

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	PAN Ming
	JIA Yan-jie

Cite this article:

PAN Ming,JIA Yan-jie. Application effect of Propofol intravenous anesthesia in patients with acute severe craniocerebral injury surgery[J]. 中国当代医药, 2019, 26(2): 183-185.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I2/183

[1]	潘丽芳.丙泊酚静脉麻醉在急性重型颅脑损伤术中的脑保护价值探讨[J].医学理论与实践，2017，30（23）：3520-3521.
[2]	王娜，刘春丽，邓爱平，等.颅脑损伤患者高凝血状态与炎性因子水平和NF-κB活性关系分析[J].疑难病杂志，2018，17（10）：1117-1121.
[3]	张玮.不同麻醉方式对重型颅脑损伤急诊手术患者的影响[J].中国现代医生，2017，55（13）：122-124.
[4]	陈帅，黄志卫，陆湛，等.早期肠内营养对重型颅脑损伤机械通气患者终点事件的影响[J].疑难病杂志，2017，16（3）：222-225.
[5]	苏亚海，张建辉，柯瑜，等.不同剂量丙泊酚静脉麻醉对急性重型颅脑损伤患者术后神经功能的影响[J].河北医药，2016，38（17）：2583-2585.
[6]	刘涛.丙泊酚静脉麻醉对急性重型颅脑损伤患者免疫功能及脑功能的影响[J].社区医学杂志，2017，15（4）：45-46.
[7]	姚琳.丙泊酚对急性重型颅脑损伤患者的脑保护作用[J].新乡医学院学报，2016，33（9）：804-806.
[8]	孙金龙.不同麻醉用药对重症颅脑损伤患者氧分压及代谢的影响[J].实用临床医药杂志，2017，21（3）：55-58.
[9]	陈登良，詹丽园.重型颅脑损伤急诊手术麻醉方式探析[J].微量元素与健康研究，2016，33（6）：6-7.
[10]	韩耀明.丙泊酚复合芬太尼麻醉对重型颅脑损伤急诊手术患者血流动力学的影响[J].中国当代医药，2016，23（18）：63-65.
[11]	吴艳，万意，贾维桂.丙泊酚联合芬太尼麻醉应用于重型颅脑损伤急诊手术患者对其脑血流动力学及认知功能的影响分析[J].临床和实验医学杂志，2017，16（22）：2209-2212.
[12]	刘俊，赵楠，李俊彦，等.持续有创颅内压监测下丙泊酚对重型颅脑损伤治疗的影响[J].大理学院学报，2016，1（8）：56-59.
[13]	刘传辉，陈浩，邱庆明，等.两种麻醉药对急性颅脑外伤患者术后血清NSE、S100B蛋白、炎性因子及认知功能的影响[J].武警医学，2017，28（9）：905-908.
[14]	张红.丙泊酚用于重型颅脑损伤并脑疝形成急症手术中的临床效果[J].中国医药指南，2017，15（18）：82-83.
[15]	祁绍艳，刘晓静，王文涛，等.舒芬太尼联合丙泊酚在重症颅脑损伤患者镇痛镇静中的应用[J].中国实用神经疾病杂志，2016，19（8）：126-127.
[16]	邱世明.丙泊酚联合舒芬太尼在重型颅脑损伤患者术后镇静镇痛中的应用[J].临床合理用药杂志，2017，10（20）：54-55.
[17]	陈笑红.丙泊酚对急性颅脑损伤手术患者的脑保护作用[J].中国实用医刊，2017，44（15）：52-54.