|
|
Clinical effect of Thiotropium Bromide assisted bronchoalveolar lavage in the treatment of bronchiectasis with pulmonary infection |
QIN Hong ZHANG Hong-bo |
Department of Respiratory Medicine,People′s Hospital of Shangrao City,Jiangxi Province,Shangrao 334000,China |
|
|
Abstract Objective To investigate the clinical effect of Thiotropium Bromide assisted bronchoalveolar lavage(BAL)in the treatment of bronchiectasis with pulmonary infection.Methods A total of 52 cases of bronchiectasis with pulmonary infection patients in our hospital from January 2016 to August 2017 were selected as the objects,all the patients were divided into the control group and the observation group according to the difference treatment methods,26 cases in each group.The control group was treated with BAL,the observation group was treated with Tiotropium Bromide assisted BAL treatment.The lung function,blood gas index and BODE index score and quality of life index(QLI)score were observed between the two groups.Results After treatment,the level of FVC,FEV1,FEV1%in the observation group were higher than those of the control group(P<0.05).The level of PaCO2 in the observation group after treatment was lower than that in the control group,the level of PaO2/FiO2 in the observation group after treatment were higher than those in the the control group(P<0.05).The BODE index score after treatment of the observation group was obviously lower than that of the control group,the QLI scores after treatment of the observation group was significantly higher than that of the control group,the differences were statistically significant(P<0.05).Conclusion Thiamethoxam bromide auxiliary BAL in the treatment of patients with pulmonary infection can effectively improve the pulmonary function,blood gas,improve the quality of life,with high clinical value.
|
|
|
|
|
[3] |
郑连云,顾学存.可必特+沐舒坦雾化吸人在支气管扩张并感染的临床观察[J].临床肺科杂志,2014,19(10):1790-1792.
|
[4] |
陈灏珠.实用内科学[M].12版.北京:人民卫生出版社,2008:1658.
|
[5] |
林卫涵.纤维支气管镜支气管肺泡灌洗并局部注药治疗支气管扩张合并感染的疗效观察[J].实用心脑肺血管病杂志,2013,21(6):85-86.
|
[6] |
吴晓晖,徐俭朴,汝触会,等.噻托溴铵粉吸入剂治疗支气管扩张症的疗效观察[J].中国现代应用药学,2013,30(5):534-537.
|
[1] |
陈昌远.支气管肺泡灌洗在支气管扩张并感染治疗中的应用[J].中国医学创新,2012,9(29):158-160.
|
[2] |
许立,张锡林.老年支气管扩张合并感染的常见病原菌及其耐药性调查[J].海南医学,2011,22(5):111-113.
|
[7] |
马艳良,何权瀛.英国胸科协会非囊性纤维化支气管扩张指南简介[J].中华结核和呼吸杂志,2011,34(11):812-815.
|
[8] |
张永庆,苗毅,尚立群,等.布地奈德福莫特罗联合噻托溴铵治疗中重度慢阻肺稳定期疗效观察[J].陕西医学杂志,2016,45(4):494-495.
|
[9] |
邱彬,陈宪明.异丙托溴铵雾化吸入为主三联治疗慢阻肺急性加重期疗效观察[J].中国药师,2015,18(12):2097-2099.
|
[10] |
彭玉超,张艳红,孟海涛.噻托溴铵粉雾剂联合阿奇霉素在支气管扩张中的应用[J].医药论坛杂志,2015,36(11):61-62.
|
[11] |
任艳平,石蕊,张睿,等.噻托溴铵治疗慢性阻塞性肺疾病有效性和安全性的Meta分析[J].中国药房,2015,26(21):2947-2949.
|
[12] |
常春,姚婉贞.噻托溴铵治疗慢性阻塞性肺疾病十年回顾与展望[J].中华结核和呼吸杂志,2016,39(3):217-220.
|
[13] |
王东升,黄昌河,毛立群.支气管肺泡灌洗治疗支气管扩张合并感染的临床疗效观察[J].中华医院感染学杂志,2011,21(11):2217-2219.
|
[14] |
刘荆湖,邹小凡.支气管肺泡灌洗治疗支气管扩张合并感染的临床效果[J].当代医学,2016,22(16):41-42.
|
[15] |
翟见喜.吸入噻托溴铵联合沙美特罗替卡松对稳定期慢性阻塞性肺疾病患者肺功能及生活质量的影响[J].社区医学杂志,2015,13(4):17-18.
|
|
|
|