AbstractObjective To explore the effect of Antelope Horn Granule in the treatment and prevention of febrile convulsion in infants.Methods A total of 80 cases of febrile convulsion infants treated in our hospital from January 2016 to January 2017 were selected.They were randomly divided into observation group and control group by random number table method,40 cases in each group.The control group was given conventional treatment,and the observation group was treated with Antelope Horn Granules on the basis of the control group.Continuous treatment until the body temperature returned to normal after 24 h.The clinical efficacy,recurrence of febrile seizures,recovery time of body temperature,relapse of body temperature and incidence of adverse reactions were observed in two groups.Results The total effective rate of the observation group was 92.5%,significantly higher than 82.5%of the control group,the difference was statistically significant(P<0.05).The recurrence rate of the observation group was significantly lower than that in the control group,and the frequency of relapse was significantly lower than that in the control group (P<0.05).There was no significant difference in the incidence rate of adverse reaction between the two groups(P>0.05).Conclusion Antelope Horn Granule is effective in the treatment of febrile convulsion in infants.It can effectively reduce the recurrence rate of convulsion,and not increase the incidence of adverse reactions.It is worthy of clinical promotion.