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Effect comparision of Modified Chaihu Shugan Powder and western medicine in the treatment of functional dyspepsia with liver depression and qi stagnation |
ZHANG Ni1 JIANG Hui-hui2 CHEN Ji-wen1 |
1.Department of Traditional Chinese Medicine,Chaozhou People′s Hospital,Guangdong Province,Chaozhou 521000,China;
2.ICU,Traditional Chinese Medicine Hospital of Yichang City,Hubei Province,Yichang 521000,China |
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Abstract Objective To compare the clinical effect of Modified Chaihu Shugan Powder and western medicine in the treatment of functional dyspepsia with liver depression and qi stagnation.Methods All of 140 patients functional dyspepsia of liver depression and qi stagnation treated in our hospital from February 2016 to May 2017 were selected and they were randomly divided into the observation group and control group,and there were 70 cases in each group.The control group was treated with Pantoprazole Enteric Capsules and Domperidone Tablets,while the observation group was treated with Modified Chaihu Shugan Powder.The clinical effect,the change of TCM syndrome score and the serum motilin and gastrin in patients of the two groups after treatment were evaluated.Results The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).Before treatment,there was no significant difference in the total score of TCM syndrome between the two groups (P>0.05).After treatment,the total score of TCM syndrome in the two groups was significantly lower than that before treatment,and the total score of TCM syndrome after treatment in the observation group was significantly lower than that of the control group (P<0.05).After treatment,serum motilin level in the two groups were significantly higher than those before treatment,and gastrin level were significantly lower than those before treatment(P<0.05).After treatment,the serum motilin level in the observation group was significantly higher than that in the control group,and the serum gastrin level was significantly lower than that in the control group(P<0.05).Conclusion Modified Chaihu Shugan Powder and western medicine in the treatment of functional dyspepsia with liver depression and qi stagnation can significantly improve TCM syndrome,promote the gastric motility and promote gastric emptying,and it is worthy of further clinical popularization.
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[1] |
张声生,赵鲁卿.功能性消化不良中医诊疗专家共识意见(2017)[J].中华中医药杂志,2017,32(6):2595-2598.
|
[2] |
黄学军,龚梅恩,罗仁浩,等.中西医结合治疗肝郁气滞型功能性消化不良的临床观察[J].中国民康医学,2007,19(7):307-308.
|
[3] |
李冀,赵志宏.柴胡疏肝散的内科临床应用研究进展[J].中医药学报,2016,44(3):117-119.
|
[4] |
夏菁,孙涛.罗马Ⅲ诊断标准的制定与功能性胃肠疾病的研究进展[J].海军总医院学报,2011,24(3):166-168.
|
[5] |
张声生,李乾构,汪红兵.消化不良中医诊疗共识意见(2009)[J].中国中西医结合杂志,2010,30(5):533-537.
|
[6] |
Eren M,ColakO,IS1ksoy S,et al.Effect of H.pylori infection on gastrin,ghrelin,motilin,and gastroesophageal reflux[J].Turk J Gastroenterol,2015,26(5):367-372.
|
[7] |
方晓琳.功能性消化不良发病机制研究进展综述[J].转化医学电子杂志,2015,2(10):117-118.
|
[8] |
张莉华,方步武.脑肠轴及其在胃肠疾病发病机制中的作用[J].中国中西医结合外科杂志,2007,13(2):199-201.
|
[9] |
冯伯林,王莉芳.功能性消化不良中西医治疗[J].中国医药指南,2012,10(9):523-524.
|
[10] |
崔月萍,沈洪.功能性消化不良的中医治疗研究进展[J].长春中医药大学学报,2011,27(6):1064-1066.
|
[11] |
胡仲纯.柴胡疏肝散的临床应用[J].现代中西医结合杂志,2008,17(18):2909-2911.
|
[12] |
范宏宇,张书文.张书文教授应用升降法治疗肝胃疾病的经验[J].陕西中医,2004,25(8):732-733.
|
[13] |
倪加哲,海英.李德新辨五脏治不寐[J].江苏中医药,2015,47(10):21-22.
|
[14] |
陈海山,龚锦容,黄朝忠,等.功能性消化不良与胃黏膜肥大细胞、血浆胃动素的关系[J].胃肠病学,2015,20(9):533-537.
|
[15] |
张洁文,孙保国,林锐珊.补中益气汤加减联合穴位敷贴治疗脾胃气虚型功能性消化不良的疗效观察及对血清胃泌素的影响[J].四川中医,2017,35(11):98-100.
|
[16] |
丁元伟,赵英恒.功能性消化不良患者胃动力、胃动素、胃泌素变化的初步探讨[J].广东医学,2000,21(2):97-98.
|
|
|
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