| [9] |
Rojas A，Jiang J，Ganesh T，et al.Cyclooxygenase-2 in epilepsy epilepsia[J].2014，55（1）：17-25.
|
| [13] |
欧阳龙强，梁日生，杨卫忠，等.黄芩苷对小鼠癫痫持续状态后海马神经细胞的保护作用[J].中华实验外科杂志，2012，29（9）：1697-1699.
|
| [1] |
Vezzani A，Fujinami RS，White HS，et al.Infections，inflammation and epilepsy[J].Acta Neuropathol，2016，131（2）：211-234.
|
| [5] |
Annamaria V，Jacqueline F，Tamas B，et al.The role of inflammation in epilepsy[J].Nat Rev Neurol，2011，7（1）：31-40.
|
| [7] |
Maria T.Hippocampal sclerosis in epilepsy：a neuropathology review[J].Neuropathol Appl Neurobiol，2014，40（5）：520-543.
|
| [2] |
Serrano GE，Lelutiu N，Rojas A，et al.Ablation of cyclooxygenase-2 in forebain neurons is neurprotective and dampens brain inflammantion after epilepticus[J].J Neurosci，2011，31（42）：14850-14860.
|
| [3] |
Bahar T，Belma K，Ayse N，et al.Contribution of iNOS/sGC/PKG pathway，COX-2，CYP4A1，and gp91phox to the protective effect of 5，14-HEDGE，a 20-HETE mimetic，against vasodilation，hypotension，tachycardia，and inflammation in a rat model of septic shock[J].Nitric Oxide，2013，33（9）：18-41.
|
| [4] |
RacineRJ，SteingartM，McintyreDC.Developmentofkindlingprone and kindling resistant rats：selective breeding and electrophysiological studies[J].Epilepsy Res，1999，35（3）：183-195.
|
| [6] |
Raimondo D，Clifford LE，Cinzia F，et al.Novel frontiers in epilepsy treatments：preventing epileptogenesis by targeting inflammation[J].Expert Rev Neurother，2013，13（6）：615-625.
|
| [8] |
Cheng O，Ostrowski RP，Wu B，et al.Cyclooxygenase-2 mediates hyperbaric oxygen preconditioning in the rat model of transient global cerebral ischemia[J].Stroke，2011，2（2）：484-490.
|
| [10] |
Jiang J，Quan Y，Ganesh T，et al.Inhibition of the protaglanin receptor EP2 following status epilepticus redcues delayed mortlity and brain inflammation[J].Proc Natl Acad Sci U S A，2013，110（9）：3591-3596.
|
| [11] |
Harumasa N，Kyungho C，Shohei S，et al.iNOS as a driver of inflammation and apoptosis in mouse skeletal muscle after burn injury：possible involvement of sirt1 S-nitrosylation-mediated acetylation of p65 NF-κB and p53[J].PLoS One，2017，12（1）：e0170391.
|
| [12] |
Iadecola C，Zhang F，Casey R，et al.Inducible nitric oxide synthase gene expression in vascular cells after transient focal cerebral ischemia[J].Stroke，1996，27（8）：1373-1380.
|
| [14] |
Park SY，Jin ML，Ko MJ，et al.Anti-neuroinflammatory effect of emodin in LPS-stimulated microglia：involvement of AMPK/Nrf2 activation[J].Neurochm Res，2016，41（11）：2981-2992.
|
| [15] |
He Y， Huang J，Wang P，et al.Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome[J].Oncotarget，2016，7（4）：4664-4679.
|
| [16] |
Yang F，Yuan PW，Hao YQ，et al.Emodin enhances osteogenesis and inhibits adipogenesis[J].BMC Complement Altern Med，2014，14：74.
|
| [17] |
顾建文，郑崇勋，杨文涛，等.大黄素对大鼠癫痈模型的脑保护作用[J].中华神经医学杂志，2006，5（7）：676-680.
|
| [18] |
Yang T，Kong B，kuang Y，et al.Emodin plays an interventional role in epileptic rats via multi-drug resistance gene 1 （MDR1）[J].Int J Clin Exp Pathol，2015，8（3）：3418-3425.
|
