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| Efficacy and safety of hormone replacement combined with local drug use in perimenopausal women with atrophic vaginitis |
| ZHONG Yan-pei |
| Department of Gynaecology,People′s Hospital of Jiangmen City,Guangdong Province,Jiangmen 529000,China |
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Abstract Objective To observe the effect of hormone replacement combined with local medication in the treatment of female atrophic vaginitis in perimenopausal women,to analyze the clinical value of hormone replacement combined with local medication,and to analyze its safety.Methods A total of 100 cases of perimenopausal women with atrophic vaginitis in our hospital from February 2014 to February 2017 were studied,patients were randomly divided into two groups,50 cases in each group.The control group was treated with local medication.The experimental group was treated with hormone replacement combined with local medication,and the effect and surface of the two groups were treated.The percentage of cells,the thickness of the endometrium,the estradiol,oestrogen and the incidence of adverse reactions after treatment were compared,and the clinical value after treatment were,and the clinical safety were also analyzed.Results The total effective rate of the experimental group was higher than the control group,the difference was statistically significant(P<0.05).The percentage of surface cells,the thickness of endometrium,estradiol and oestrogen after treatment were perfected,and the experimental group was higher than those in the control group,the differences were statistically significant(P<0.05);the adverse reaction rate was compared with the experimental group,the difference was statistically significant(P<0.05).Conclusion For the patients with perimenopausal atrophic vaginitis,the use of hormone instead of local medication is safer and more effective and suitable for future clinical related treatment.
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