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Effect of potassium Sodium Dehydroandroan drographolide Succinate combined with interferon inhalation in treatment of children with herpangina |
JIANG Xia |
Department of Pediatrics,People′s Hospital of Naxi District of Luzhou City,Sichuan Province,Luzhou 646300,China |
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Abstract Objective To probe into the clinical effects of potassium Sodium Dehydroandroan drographolide Succinate combined with interferon inhalation in treatment of children with herpangina.Methods 78 cases of children with herpangina and who accepted treatments in our hospital from May 2014 to March 2016 were selected as the research object,and were randomly divided into observation group(37 cases)and control group(39 cases)by the random digit table grouping method.Patients of the two groups were treated with conventional therapy,on the basis of conventional treatmen,the control group were treated with Ribavirin while in the observation group,on the basis of the treatment in the control group,they were treated with potassium Sodium Dehydroandroan drographolide Succinate combined with interferon inhalation.Then,the clinical effects,symptom disappearance time,rate of adverse reaction and so on of two groups were observed.Results The total effective rate of the observation group was 94.87%,which was significantly higher than that in the control group (76.92%),the difference was statistically significant(P<0.05);the salivation disappeared time, herpes disappear time,pyretolysis time,healing time in the observation group after treatment was significantly shorter than the control group respectively,the difference was statistically significant(P<0.05);the incidence of adverse reactions in the observation group after treatment was 7.69%,while in the control group was 28.21%,the difference between the two groups was statistically significant(P<0.05).Conclusion The effect of potassium Sodium Dehydroandroan drographolide Succinate combined with interferon inhalation in treatment of children with herpangina is satisfactory,which can shorten the recovery the time of symptoms and signs,promote the rehabilitation of the disease,but also with high safety,thus it is worthy to be promoted in the clinical.
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[1] |
陈纯.疱疹性咽峡炎的临床和流行病学特征[J].国际流行病学传染病学杂志,2016,43(4):270-273.
|
[2] |
夏蝉,余坚,金龙腾,等.疱疹性口炎与疱疹性咽峡炎的病原学检测[J].中华全科医学,2016,14(10):1719-1722.
|
[3] |
王玉洁,杨洪,姚相杰,等.2015年深圳地区疱疹性咽峡炎的病原学与流行病学特征分析[J].中华疾病控制杂志,2016,20(8):759-763.
|
[4] |
牛伟红,杨丽萍,刘彦霞,等.不同方法治疗疱疹性咽峡炎的疗效分析[J].河北医科大学学报,2014,35(1):80-82.
|
[5] |
曹兴丽.热毒宁注射液联合利巴韦林气雾剂治疗小儿疱疹性咽峡炎的疗效观察[J].临床和实验医学杂志,2011,10(21):1705-1706.
|
[6] |
刘牧,王彬,高晓凤,等.疱疹性咽峡炎发展为手足口病患儿早期临床表现分析[J].中国综合临床,2014,30(3):329-331.
|
[7] |
张喜芳.手足口病流行期疱疹性咽峡炎80例临床分析[J].中国实用医刊,2015,42(24):66-67.
|
[8] |
陈向前,施学文,曹青,等.手足口病流行期疱疹性咽峡炎的病原及临床分析[J].临床儿科杂志,2013,31(5):429-432.
|
[9] |
牛伟红,杨丽萍,秦明月,等.150例疱疹性咽峡炎临床资料总结及分析[J].中国医药导刊,2014,16(4):661-662.
|
[10] |
吴高华,陈富超,李鹏,等.炎琥宁与利巴韦林治疗儿童疱疹性咽峡炎疗效的Meta分析[J].现代中西医结合杂志,2013,22(8):821-823.
|
[11] |
潘锋君,吴小芬,田伟强,等.蓝芩口服液联合干扰素雾化吸入治疗小儿疱疹性咽峡炎[J].中国药师,2015,18(2):283-285.
|
[12] |
杨丽萍,王敬君.核黄素磷酸钠联合干扰素α1b治疗疱疹性咽峡炎的临床观察[J].海南医学,2016,27(6):1005-1006.
|
[13] |
孙丽丽.重组人干扰素α1b亚型治疗小儿疱疹性咽峡炎的疗效及安全性观察[J].中国临床研究,2013,26(2):153-154.
|
[14] |
赵德春,徐能潮,王军,等.炎琥宁联合α干扰素治疗小儿急性上呼吸道感染效果观察[J].中国妇幼健康研究,2015,26(3):566-567.
|
[15] |
朱庆龄,杨声坪,叶新华,等.炎琥宁对比利巴韦林治疗小儿疱疹性咽峡炎疗效和安全性的系统评价[J].儿科药学杂志,2014,20(4):4-9.
|
|
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