2012～2015年福建宁德地区手足口病流行病学分析

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Abstract Objective To investigate the epidemiological characteristics of hand-foot-mouth disease in Ningde area, Fujian province from 2012 to 2015.Methods The information system of China CDC was applied.The epidemiological data were used to statistically analyze the monitoring data and pathogenicity results of hand-foot-mouth disease in Ningde area,Fujian province from 2012 to 2015.Real-time fluorescence quantitative polymerase chain reaction was used to test EV71 virus,coxsackievirus A16,and other enteroviruses.Results The incidence of hand-foot-mouth disease in Ningde area of Fujian Province was analyzed.From 2012 to 2015,the number of incidence was in a reducing trend. The number of severe cases and the number of deaths were significantly reduced in 2013.Severe disease rates,mortality rate,and mortality rate of severe diseases were fluctuating.The laboratory diagnosis composition ratio of severe patients was higher than that in the normal patient(P<0.05).The laboratory diagnosis composition ratio of deceased patients was higher than that in the normal patients and severe patients(P<0.05).The composition ratio of EV71 virus in severe patients and deceased patients was higher than that of coxsackievirus A16 and other enteroviruses (P<0.05).The number of patients in rural area was higher,and the incidence rate of severe diseases,mortality rate and mortality of severe diseases were higher in rural areas than in urban areas(P<0.05).Conclusion The number of hand-foot-mouth disease in Ningde area of Fujian province is in a decreasing trend from 2012 to 2015,and incidence rate of severe diseases and mortality rate,although fluctuating,still remain in a low level.

Key words： Hand-foot-mouth disease EV71 virus Coxsackievirus A16 Epidemiological methods

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	LIN Hou-xiong
	WANG De-zhi

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LIN Hou-xiong,WANG De-zhi. Epidemiological analysis of hand-foot-mouth disease in Ningde district in Fujian province from 2012 to 2015[J]. 中国当代医药, 2017, 24(9): 157-159.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I9/157

[1]	李国英，李润青，张晓慧，等.肠道病毒71型和柯萨奇病毒A组致手足口病临床特点分析[J].中国全科医学，2012，15（11）：1271-1272.
[2]	余雄武，冯琳，潘虹，等.实时荧光RT-PCR法检测手足口病病原体EV71和CA16及临床特点分析[J].中国妇幼保健，2016，31（2）：408-410.
[3]	郑书发，崔大伟，余斐，等.浙江省杭州地区手足口病病原谱分析和肠道病毒71型VP1基因分析[J].现代预防医学，2011，38（2）：305-308，311.
[4]	宋春兰，郭燕军，成怡冰，等.合并神经损害的危重型手足口病患儿临床特征及预后分析[J].郑州大学学报（医学版），2015，50（1）：128-130.
[5]	李建明，刘映霞，林益敏，等.258例手足口病中枢神经系统并发症的临床特征及预后分析[J].中华实验和临床病毒学杂志，2014，28（4）：241-244.
[6]	卢秀兰，左超，仇君，等.氨基末端脑钠肽前体对重症手足口病患儿病情及预后评估的意义[J].中华实用儿科临床杂志，2015，30（10）：750-753.
[7]	卫生部.2008年手足口病预防控制指南[J].中华实验和临床感染病杂志（电子版），2008，2（3）：210-213.
[8]	俞蕙.儿童手足口病重症病例的临床早期识别[J].中华儿科杂志，2012，50（4）：284-285.
[9]	嵇红，李亮，吴斌，等.江苏省2008至2010年手足口病流行病学及病原学特征分析[J].中华儿科杂志，2012，50（4）：261-266.
[10]	钱海坤，田祎，李锡太，等.2007-2012年北京市手足口病流行病学研究[J].国际病毒学杂志，2013，20（1）：6-10.
[11]	常昭瑞，张静，孙军玲，等.中国2008-2009年手足口病报告病例流行病学特征分析[J].中华流行病学杂志，2011，32（7）：676-680.
[12]	陈清.IL-6和IL-13与EV71型肠道病毒感染手足口病患者发病的相关性[J].重庆医学，2015，44（26）：3634-3636.
[13]	王忠敏，滕淑，邵启民，等.EV71病毒载量与手足口病病情严重程度的相关性[J].浙江临床医学，2014，16（11）：1723-1725.
[14]	游彩玲，王金华，陈秀清，等.TORCH感染与不良妊娠结局的关系[J].中国人兽共患病学报，2010，26（7）：712-713.
[15]	姜海利，王小新，路畅，等.柯萨奇病毒宫内感染的临床分析[J].中国临床医生杂志，2016，44（3）：90-92.