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| Application effects of combined with Pulmicort aerosol inhalation in prevention pulmonary infection after hypertensive cerebral hemorrhage operation at perioperative period |
| LI Jie LONG Xiao-ao▲ LI Li-qiu LIN Heng |
| Department of Neurosurgery,Hospital Affiliated to Guangdong Medical University,Guangdong Province,Zhanjiang 524000,China |
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Abstract Objective To observe the effects of combined with Pulmicort aerosol inhalation in prevention pulmonary infection at perioperative period of hypertensive cerebral hemorrhage,and to further explore the clinical effects of Pulmicort in prevention pulmonary infection.Methods 128 hypertensive cerebral hemorrhage patients who needed to craniotomy for removal of hematoma from January 2013 to June 2016 were selected and divided into the treatment group and the control group.68 patients in the treatment group were used Pulmicort 2 mg combined with Ambroxol Hydrochloride 30 mg aerosol inhalation for 3 times a day from hospitalized to 10 days after operation,60 patients in the control group were used Ambroxol Hydrochloride 30 mg aerosol inhalation for 3 times a day.The level of PaCO2,PaO2,OI and pulmonary infection situation at 1st,5thand 10thdays postoperative in the two groups were compared.Results The level of PaCO2,PaO2and OI in the treatment group at 5thand 10thdays after operation were improved than those in the control group,and the difference was statistical significance(P＜0.05).The incidence rate of postoperative pulmonary infection in the treatment group was 38%,which was lower than that in control group (58%),with significant difference(P＜0.05). Conclusion Pulmicort combined with Ambroxol Hydrochloride aerosol inhalation at perioperative period of hypertensive cerebral hemorrhage can prevent pulmonary infection effectively by enhancing PaO2and decreasing PaCO2,improving oxygenation of organs and tissues.
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