经皮胆道金属支架治疗术对肝门部胆管癌患者的临床效果

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Abstract ObjectiveTo investigate the clinical effect of percutaneous biliary metal stenting in patients with hilar cholangiocarcinoma.MethodsA total of 62 patients with hilar cholangiocarcinoma who had lost the opportunity of surgical resection from January 2011 to December 2014 were selected.Percutaneous biliary metal stenting was carried out under the guidance of ultrasonography.After 1 week,the biliary metal stent implantation was performed under DSA fluoroscopy.The external drainage in the percutaneous biliary metal stenting was switched into the internal drainage within biliary stent.ResultsA total of 56 patients with hilar cholangiocarcinoma out of 62 patients were successfully implanted with biliary stent.The success rate was 90.3% .The serum total bilirubin in 56 patients with hilar cholangiocarcinoma was decreased from (290.3±170.0)μmol/L before the surgery to (108.2±62.0)μmol/L.The serum direct bilirubin was decreased from(197.3±119.2)μmol/L before the surgery to(49.2±19.4)μmol/L.Alanine aminotransferase was decreased from (206.3±127.4)U/L to (80.1±55.8)U/L after the surgery.Aspartate aminotransferase was decreased from (180.1±95.2)U/L to (94.2±59.7)U/L after the surgery.γ－glutamyl transpeptidase was decreased from (756.8±302.1)U/L to(230.1± 101.5)U/L.AFP was decreased from(120.3±32.2)μg/L to(98.2±10.8)μg/L.All the differences were statistically significant(P＜0.05).ConclusionPercutaneous biliary metal stenting can effectively improve the liver function of patients with hilar cholangiocarcinoma， which is worthy of clinical promotion and application.

Key words： Hilar cholangiocarcinoma Percutaneous biliary metal stenting Alpha－fetoprotein &gamma －glutamyl transpeptidase

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	SHEN Bo
	LUO Jun-feng
	PAN Jing-gang
	ZHANG Yu-ting

Cite this article:

SHEN Bo,LUO Jun-feng,PAN Jing-gang, et al. Clinical effect of percutaneous biliary metal stenting on hilar cholangiocarcinoma[J]. 中国当代医药, 2017, 24(29): 56-58.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I29/56

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