|
|
Study on thecorrelation between bodymassindex,endocrineand metabolic abnormalities in patients with polycystic ovary syndrome |
HE Xiao-jie1 GU Dong-hai1 LI Ri-shao2 HE Guo-feng1 |
1.Department of Endocrinology,People′s Hospital of Maoming City in Guangdong Province,Maoming 525000,China;
2.Department of Hand and Foot Microsurgery,People′s Hospital of Maoming City in Guangdong Province,Maoming 525000,China |
|
|
Abstract ObjectiveTo investigate the correlation between body mass index,endocrine and metabolic abnormalities in patients with polycystic ovary syndrome(PCOS).MethodsFrom July 2014 to July 2016,90 patients with PCOS were selected and divided into the<23 kg/m2group(43 cases),the 23-25 kg/m2group(21 cases),the>25 kg/m2group(26 cases) according to body mass index(BMI).The indexes of insulin(INS),endocrine and metabolism in each group were tested.ResultsThe total testosterone (T)and INS levels in the<23 kg/m2group were lower than those in the other two groups (P<0.05),and the level of T and INS in>25 kg/m2group was relatively highest.Compared with the<23 kg/m2group,the level of T in the other two groups increased by 1.65(95%CI:1.33-2.06)and 4.26(95%CI:2.16-8.37)times;and the insulin resistance index(HOMA-IR)increased by 1.69(95%CI:1.42-2.00)and 4.46(95%CI:2.57-7.75)times.ConclusionObese PCOS patients are accompanied by severe endocrine disorder and metabolic disorde,and need symptomatic treatment and weight control.
|
|
|
|
|
[1] |
陶弢,刘伟,赵爱民,等.不同表型多囊卵巢综合征患者代谢综合征患病特点及风险研究[J].中华内分泌代谢杂志,2013,29(3):200-205.
|
[2] |
王立斌.不同体重多囊卵巢综合征患者内分泌和代谢指标相关分析[J].当代医学,2011,17(4):85-87.
|
[3] |
Kauffman RP,Baker TE,Graves-Evenson K,et al.Lipoprotein profiles in Mexican American and non-Hispanic white women with polycystic ovary syndrome[J].Fertil Steril,2011,96(6):1503-1507.
|
[4] |
徐碧红,张凤.肥胖与非肥胖多囊卵巢综合征患者内分泌激素对比研究[J].华南国防医学杂志,2011,25(5):446-447.
|
[5] |
Wild RA.Dyslipidemia in PCOS[J].Steroids,2012,77(4):295-299.
|
[6] |
谢铁男,岳瑛,张利群.多囊卵巢综合征胰岛素抵抗的临床研究[J].中国妇幼保健,2012,27(5):679-681.
|
[7] |
陶弢,刘伟,毛家亮,等.二甲双胍短期治疗对多囊卵巢综合征患者心理异常和代谢特征的影响[J].中华内分泌代谢杂志,2013,29(3):211-215.
|
[8] |
赵庆红,石华,杨菁,等.多囊卵巢与多囊卵巢综合征的超声特征和激素水平相关性分析[J].中华全科医师杂志,2014,13(1):57-59.
|
[9] |
崔琳琳,陈子江.多囊卵巢综合征诊断标准和诊疗指南介绍[J].国际生殖健康/计划生育杂志,2011,30(5):405-408.
|
[10] |
洪宇,刘雯,赵晓苗,等.多囊卵巢综合征患者的血脂代谢异常及与胰岛素抵抗的关系分析[J].实用妇产科杂志,2012,28(3):230-233.
|
[11] |
Jayagopal V,Kilpatrick ES,Holding S,et al.The biological variation of insulin resistance in polycystic ovary syndrome [J].Clin Endocrinol Metab,2002,87(4):1560-1562.
|
[12] |
洪丽华.肥胖与非肥胖多囊卵巢综合征患者血清基础黄体生成素水平分析[J].全科医学临床与教育,2015,13(5):569-571.
|
[13] |
刘进,杨艳玲,刘建国.胰岛素抵抗与非胰岛素抵抗多囊卵巢综合征的临床治疗对比研究[J].中国妇幼保健,2012,27(36):5915-5916.
|
[14] |
赵正云,沈冰珊,李小玲,等.多囊卵巢综合征患者胰岛素抵抗特征及相关因素研究[J].中国全科医学,2011,14(24):2722-2723.
|
[15] |
陆新虹,杨海燕,罗佐.不同胰岛素抵抗状态下多囊卵巢综合征患者内分泌指标与卵巢超声特征的相关性研究[J].中国糖尿病杂志,2015,23(1):40-42.
|
|
|
|