CRP、D-二聚体和BNP浓度与急性肺栓塞患者不良事件相关性研究

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (36 KB)
Export: BibTeX | EndNote (RIS)

Abstract ObjectiveTo investigate the clinical value of C reactive protein (CRP),D-dimer(DD)and brain natriuretic peptide(BNP)in the short-term prognosis of acute pulmonary embolism(PE).Methods30 cases treated in our respiration medicine from October 2014 to October 2016 of acute pulmonary embolism patients were divided into high concentration group(DD＞5000 ns／ml,CRP＞10 mg/L,BNP＞500 ng/L)and low concentration group(DD＜4999 ns/ml,CRP＜10 mg/L,BNP＜500 ng/L),15 cases in each group.The adverse eventin the two groups was recorded and analyzed during treatment and after 3 months.Logistic linear regression analysis was used to analyze the correlation between the concentration of CRP,DD,BNP and adverse event.ResultsThe number of deaths within 3 months in the high concentration group was significantly higher than that of the low concentration group,the difference was statistically significant(P＜0.05);The concentration of CRP,BNP in dead patients was significantly higher than those of the survived patients,the difference was statistically significant(P＜0.05).While the concentration of DD in two groups had no statistically difference（P＞0.05）.Logistic linear regression analysis showed that the concentration blood CRP,BNP,DD level before treated had a high correlation with death.ConclusionThe concentration of CRP,DD and BNP before treated has a high clinical value in the short-term prognosis of acute pulmonary embolism,and it is worth promoting.

Key words： Acute pulmonary embolism C reactive protein D-dimer Brain natriuretic peptide Prognosis evaluation

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LENG Wen-wen
	ZHANG Chao
	ZHAO Xuan

Cite this article:

LENG Wen-wen,ZHANG Chao,ZHAO Xuan. Study on the correlation between serum CRP,DD,BNP and adverse events in patients with acute pulmonary embolism[J]. 中国当代医药, 2017, 24(17): 30-32.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I17/30

[1]	袁连方，戴璇，胡国华，等.急性肺栓塞的诊断及治疗进展[J].中华肺部疾病杂志，2014，7（5）：578-580.
[2]	韩丽丽，张永祥，赵莹，等.血清BNP、TnI及D-二聚体水平对急性肺栓塞患者病情及预后评估的价值[J].山东医药，2016，56（44）：92-94.
[3]	杨俊.血浆BNP、D-二聚体及cTnI水平检测在急性肺栓塞诊断中的价值分析[J].医技与临床，2016，14（2）：60-61.
[4]	刑国燕，赵树波.急性肺栓塞患者血D-二聚体、B型钠尿肽、肌钙蛋白I、C反应蛋白的研究[J].中国当代医药，2016，23（3）：28-30.
[5]	孟燕，出红燕，马强，等.C反应蛋白在肺栓塞患者的临床价值[J].中华全科医学，2012，10（3）：349-350.
[6]	耿红霞.血浆脑钠肽、肌钙蛋白I联合D-二聚体检测在急性肺栓塞中的意义[J].贵阳医学院学报，2015，40（10）：1063-1065.
[7]	张凤.纤维蛋白原和D-二聚体检测在肺栓塞诊断中的价值[J].中国实用医刊，2014，41（3）：122-123.
[8]	徐萍芳，周伟英.肺栓塞治疗的研究进展[J].心血管病学进展，2015，36（3）：269-272.
[9]	狄鸿胜，刘淑芹.急性肺栓塞的临床特点与早期预防性诊断[J].吉林医学，2012，3（14）:2999-3000.
[10]	金其花，吴文娟，海冰，等.血浆脑钠肽、肌钙蛋白I联合D-二聚体检测在急性肺栓塞中的临床意义[J].云南医药，2014，35（1）：2-5.
[11]	吕亚辉，李杰.联合检测BNP、TNI、CRP及D-二聚体在肺栓塞患者中的诊断、病情判定及预后的指导意义[J].中国医药导刊，2014，16（10）：1290-1292.
[12]	方建江，李波，何旭娟，等.血浆肌钙蛋白I、B型钠尿肽及D-二聚体检测在急性肺栓塞预后评估中的意义[J].中国呼吸与危重监护杂志，2012，11（1）：61-64.
[13]	俊琴，何月敬，黄慧萍.血浆D-二聚体、纤维蛋白原联合检测在急性肺栓塞中的诊断价值[J].中国现代医生，2011，49（35）：64-65.
[14]	于丽娜，李琳，张劲松.肌钙蛋白T和脑利钠肽对急性肺栓塞患者病情和预后评价的临床研究[J].南京医科大学学报，2012，32（1）：82-85.
[15]	叶巧国，薛国平，张三武，等.D-二聚体、CRP和BNP检测在肺栓塞临床诊断中的应用[J].热带医学杂志，2016，16（4）：503-505.