|
|
Analysis of effects of Sodium Hyaluronate on preventing adhesion after tendon suture |
CHEN Ming-jin |
Department of Emergency,Hospital of Shishi City in Fujian Province,Shishi 362700,China |
|
|
Abstract ObjectiveTo investigate the preventive effect of Sodium Hyaluronate on adhesion after tendon suture and the influence of hand function.Methods74 patients with hand injuries accompanied by rupture at least 1 extensor tendons or flexor tendons from March 2014 to December 2016 in our hospital were selected as the subjects,all patients were divided into the control group (27 cases of extensor tendon,10 cases of flexor tendon)and the treatment group(27 cases of extensor tendon,10 cases of flexor tendon)according to random control and voluntary principle,37 cases in each group.The control group was treated with modified Kessler suture,and no Sodium Hyaluronate.The treatment group was treated with modified Kessler suture,and sodium hyaluronate was used to suture the tendon suture,or Sodium Hyaluronate was injected into the tendon sheath,all patients were observed and recorded in 1,2,3 months after the finger total activity(TAM),and clinical effect of the treatment of flexor tendon rupture were recorded at the same time,the complications of tendon adhesion were compared after 3 months.ResultsThe TAM of the fingers in the two groups after 1,2 and 3 months was higher than that before the treatment,with significant difference(P<0.05).The TAM of the fingers in the treatment group after 1,2 and 3 months was higher than that of the control group,with significant difference (P<0.05).The excellent and good rate of extensor tendon and flexor tendon in the treatment group after 3 months was higher than that in the control group,with significant difference(P<0.05).The adhesion rate of the treatment group was 5.40%,which was lower than 27.02%of the control group,with significant difference(P<0.05).ConclusionSodium Hyaluronate can effectively relieve tendon adhesion,promote postoperative recovery,improve the quality of life of patients,and no obvious adverse reaction,it is worthy of clinical promotion and application.
|
|
|
|
|
[1] |
唐延军,李玉梅.吻合口无结Kessler缝合法修复指屈肌腱的疗效观察[J].中国修复重建外科杂志,2011,25(10):1210-1213.
|
[2] |
郭良玉.指屈肌腱缝合早期控制下活动预防肌腱粘连54例分析[J].中国误诊学杂志,2010,10(3):659-660.
|
[3] |
程敏,矢庆明,冯琼.玻璃酸钠在预防伸指肌腱修复术后粘连中的应用[J].实用临床医学,2008,9(5):77.
|
[4] |
马子杰.透明质酸钠预防屈指肌腱断裂术后粘连的疗效分析[J].河南外科学杂志,2013,19(5):104-105.
|
[5] |
王澍寰.手外科学[M].北京:人民卫生出版社,2011.
|
[6] |
李庆泰,田光磊.手外科诊断学[M].北京:人民卫生出版社,2009.
|
[7] |
潘达德,顾玉东,侍德,等.中华医学会手外科学会上肢部分功能评定使用标准[J].中华手外科杂志,2000,16(3):130-135.
|
[8] |
王韶进,戴国锋,李昕,等.透明质酸钠预防屈肌腱粘连的临床研究[J].中国修复重建外科杂志,2002,16(1):28-30.
|
[9] |
单海民,程春生,李刚,等.Ⅰ型牛胶原蛋白生物膜预防屈指肌腱损伤术后粘连的临床研究[J].中医正骨,2012,24(12):27-29.
|
[10] |
张健生,杨日新,朱菁锋,等.急诊手外伤术后肌腱粘连的原因分析与早期防治策略[J].中外医学研究,2015,13(20):14-16.
|
[11] |
赵序东,段大航.药物预防治疗手部肌腱断裂术后粘连[J].内蒙古中医药,2014,33(32):110-111.
|
[12] |
庞有明,丰波,张霄雁.玻璃酸钠对预防指屈肌腱粘连的临床研究[J].中国冶金工业医学杂志,2012,29(5):587-588.
|
[13] |
Wei G,Zhou C,Wang G,et al.Keratinocyte growth factor combined with a Sodium Hyaluronate Gel inhibits postoperative intra-abdominal adhesions[J].Int J Mol Sci,2016,17(10):E1611.
|
[14] |
张健生,朱菁锋,杨日新,等.普理灵缝线缝合配合功能锻炼预防手屈肌腱断裂术后肌腱粘连的研究[J].中国处方药,2014,12(7):116-117.
|
[15] |
糜检,李木清,田涛涛.中药熏洗配合功能锻炼预防手屈肌腱断裂术后肌腱粘连[J].中国中医药现代远程教育,2013,11(1):15-16.
|
[16] |
Hu J,Fan D,Lin X,et al.Safety and efficacy of Sodium Hyaluronate Gel and Chitosan in preventing postoperative peristomal adhesions after defunctioning enterostomy[J].Medicine,2015,94(51):e2354.
|
|
|
|