|
|
Effect of conventional treatment combined with lung surface active substance in the treatment of premature infant respiratory distress syndrome |
CHEN Shao-li QIAO Ping WANG Wei-ming LI Jin-wen |
Department of Neonatology,the First People′s Hospital of Zhaoqing City,Guangdong Province,Zhaoqing 526000,China |
|
|
Abstract ObjectiveTo study the conventional treatment combined with lung surface active substance in the treatment of premature infant respiratory distress syndrome.MethodsFrom February 2008 to February 2016,100 cases of children with premature respiratory distress syndrome were selected and randomly divided into observation group and the control group,50 cases in each group.Control group was given conventional treatment,and the observation group was given the lung surface active substance on the basis of the control group.The blood gas and oxygenation function index before and after treatment,and time of mechanical ventilation,oxygen therapy after treatment,length of hospital stay and clinical effect of children were compared between the two groups.ResultsAfter treatment,blood gas and oxygenation function index of the observation group were better than those of the control group(P<0.05);the time of mechanical ventilation,oxygen therapy after treatment,length of hospital stay of the observation group were shorter than those of the control group (P<0.05);the treatment effect of observation group was obviously better than that of control group (P<0.05).ConclusionIn treatment of premature infant respiratory distress syndrome,the lung surface active substance has shorten the length of hospital stay,time of oxygen therapy and mechanical ventilation,and has obviously improved the lood gas and oxygenation function,treatment effect is remarkable,it is worthy of further application in clinic.
|
|
|
|
|
[6] |
田喜军,丛力宁,杨娅丽,等.应用外源性肺表面活性物质治疗新生儿呼吸窘迫综合征的临床X线变化及诊断[J].河北医药,2014,32(18):2510-2512.
|
[7] |
黄建平,樊秋明.固尔苏预防新生儿呼吸窘迫综合症临床研究[J].国际医药卫生导报,2014,14(7):43.
|
[8] |
张德凤,潘家华.固尔苏预防新生儿呼吸窘迫综合症的疗效分析[J].临床肺科杂志,2013,14(3):303-312.
|
[1] |
杨一民,李蕙,陈四文,等.肺表面活性物质治疗早产儿呼吸窘迫综合征及其影响机械辅助通气方式的临床研究[J].中国全科医学,2016,14(3):3807-3810.
|
[2] |
江金彪,邵爱华,陈弘,等.NCPAP联合肺表面活性物质治疗早产儿呼吸窘迫综合征的疗效观察[J].中国妇幼保健,2014,29(5):724-725.
|
[4] |
何丽红,陈爱贞,王丽容.肺表面活性物质预防早产儿呼吸窘迫综合征疗效观察[J].实用儿科临床杂志,2016,18(10):782-783.
|
[5] |
黄润忠,黄建伟,苏永棉,等.肺表面活性物质及鼻塞CPAP治疗早产儿呼吸窘迫综合征[J].中国妇幼保健,2015,30(8):83-84.
|
[3] |
Sweet DG,Halliday HL,Speer CP.Surfactant therapy for neonatal respiratory distress syndrome in 2013[J].J Matern Fetal Neonatal Med,2013,26(24):27-29.
|
[9] |
杨宁,阳宇,王大果.肺表面活性物质治疗新生儿呼吸窘迫综合症的临床观察[J].中国医疗前沿,2015,6(2):50-55.
|
[10] |
Cogo PE,Facco M,Simonato M,et al.Dosing of porcinesurfactant:effect on kinetics and gas exchange in respiratory distress syndrome[J].Pediatrics,2013,124(5):e950-e957.
|
[11] |
齐荣,李园,唐瑾,等.肺表面活性物质与盐酸氨溴索治疗新生儿肺透明膜病疗效比较[J].疑难病杂志,2016,15(5):510-513,524.
|
[12] |
杨娟,柏进,周婷,等.不同通气方式联合肺表面活性物质治疗新生儿呼吸窘迫综合征疗效评价[J].山东医药,2014,50(9):74-75.
|
[13] |
许航燕,陈荣昌.鼻塞持续正压通气联合肺表面活性物质治疗新生儿呼吸窘迫综合征的临床效果观察[J].中国医药导报,2013,10(25):36-38.
|
[14] |
柏进,杨娟,高凤,等.肺表面活性物质治疗新生儿呼吸窘迫综合征的临床观察[J].中国妇幼保健,2014,29(28):4062-4064.
|
[15] |
张丹丹.肺表面活性物质联合鼻塞持续正压通气治疗新生儿呼吸窘迫综合征临床分析[J].母婴世界,2015,(20):37.
|
[16] |
刘光辉,张健,卢林阳.应用肺表面活性物质联合NCPAP治疗早产儿呼吸窘迫综合征的对照研究[J].临床肺科杂志,2012,17(1):35-37.
|
[17] |
郑如.肺表面活性物质联合机械通气治疗新生儿呼吸窘迫综合征的护理配合[J].中外健康文摘,2012,9(23):138-139.
|
|
|
|