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Clinical effect of sequential mechanical ventilation on severe pneumonia complicated with respiratory failure |
ZENG Wei-jian |
Respiratory Intensive Care Unit,People′s Hospital of Meizhou City in Guangdong Province,Meizhou514031,China |
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Abstract Objective To explore clinical effect of sequential mechanical ventilation on severe pneumonia complicated with respiratory failure.Methods Clinical data of 224 patients with severe pneumonia complicated with failure respiration in our hospital from December 2014 to December 2015 were analyzed,which was divided into two groups by different treatment methods,control group(invasive mechanical ventilation treatment)104 cases and observation group(sequential mechanical ventilation treatment)120 cases.Invasive ventilation time,total mechanical ventilation time,length of hospital stay(LOS),incidence rate and mortality of respiratory associated pneumonia,HR,RR,PaCO2,PaO2when in group and PIC were observed.Results Invasive ventilation time,total mechanical ventilation time,LOS,incidence rate and mortality of respiratory associated pneumonia in the observation group was lower than that in the control group,and the difference was statistical significance(P<0.05).HR,RR,PaCO2,PaO2between two groups when in group had no difference (P>0.05).PaO2PaCO2between two groups when PIC had no difference(P>0.05);HR,RR in the observation group was lower than that in the control group when PIC,and the difference was statistically significant(P<0.05).HR,RR,PaCO2in two groups when PIC was lower than that when in group,and the difference was statistical significance(P<0.05);there was no significant difference in two groups in PaO2when PIC compared with when in group(P>0.05).Conclusion Sequential mechanical ventilation in the treatment of patients with severe pneumonia compared with failure respiration can shorten ventilation time and improve obviously hemodynamics,it is worth to be used.
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[1] |
张海光,邓克勤,陈玮,等.序贯机械通气治疗重症肺炎患者呼吸衰竭的疗效[J].中华医院感染学杂志,2015,25(14):3224-3228.
|
[2] |
张雪彦,赵晔.有创-无创序贯机械通气治疗AECOPD合并Ⅱ型呼吸衰竭的临床研究[J].临床肺科杂志,2012,17(3):420-421.
|
[3] |
张龄幻,于艳辉,朱晓萍.重症肺炎合并心力衰竭患儿血清肌酸激酶同工酶、脑利钠肽及神经肽Y水平变化[J].临床儿科杂志,2015,33(6):539-542.
|
[4] |
Zhang Z,Cai CX.Kidney injury molecule-1(KIM-1)mediates renal epithelial cell repair via ERK MAPK signaling pathway[J].Mol Cell Biochem,2016,416(1-2):109-116.
|
[5] |
徐惠良.鼻塞式持续呼吸道正压给氧在小儿重症肺炎合并呼吸衰竭中的临床应用价值分析[J].中国妇幼保健,2011,26(34):5342-5344.
|
[6] |
Nojiri T,Inoue M,Shintani Y,et al.B-type natriuretic peptideguided risk assessment for postoperative complications in lung cancer surgery[J].World J Surg,2015,39(5):1092-1098.
|
[7] |
李翠.有创无创序贯机械通气抢救重症老年呼吸衰竭患者的有效性与安全性[J].中国老年学杂志,2014,34(17):4818-4820.
|
[8] |
García Vicente E,Sandoval Almengor JC,Díaz Caballero LA,et al.Invasive mechanical ventilation in COPD and asthma[J].Med Intensiva,2011,35(5):288-298.
|
[9] |
傅向东,张婕,雷琳,等.有创与无创序贯机械通气治疗肺结核并严重呼吸衰竭的临床研究[J].河北医学,2013,19(8):1160-1162.
|
[10] |
Farah R,Makhoul N.Optimal time needed for withdrawal of mechanical ventilation in patients with chronic obstructive pulmonary disease[J].Isr Med Assoc J,2011,13(10):609-612.
|
[11] |
李艳.不同时间采用NPPV治疗COPD合并呼吸衰竭的疗效观察[J].西南国防医药,2014,24(5):486-489.
|
[12] |
Shelhamer MC,Rowan MP,Cancio LC,et al.Elevations in inflammatory cytokines are associated with poor outcomes in mechanically ventilated burn patients[J].J Trauma Acute Care Surg,2015,79(3):431-436.
|
[13] |
冯丽,张育红,王萍,等.无创双水平正压通气治疗慢性阻塞性肺疾病合并肺性脑病的护理探讨[J].中国临床医学,2014,21(2):223-225.
|
[14] |
Espunias AM,Ucar ZZ,Kirakli C.Deventilation syndrome in severe COPD patients during long-term noninvasive mechanical ventilation:poor sleep pattern,hyperinflation,or silent chronic muscular fatigue[J].Sleep Breath,2014,18(2):225-226.
|
[15] |
Frazier SB,Sepanski R,Mangum C,et al.Association of systemic inflammatory response syndrome with clinical outcomes of pediatric patients with pneumonia[J].South Med J,2015,108(11):665-669.
|
[16] |
陈德勇,孙晓云,黎晓强.慢性阻塞性肺疾病急性加重期患者撤机困难的临床分析[J].现代医院,2015,15(6):37-38.
|
[17] |
顾新南,蒋建中.无创正压通气联合呼吸兴奋剂治疗慢性阻塞性肺疾病急性加重期合并轻中度肺性脑病的疗效分析[J].江苏医药,2012,38(21):2599-2601.
|
[18] |
赖建幸,陈小会.无创正压通气治疗慢性阻塞性肺疾病急性加重期呼吸衰竭的临床研究[J].中国现代医生,2014,52(4):7-10.
|
|
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