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Determination of calcitonin original application in patients with syphilis diagnosis and treatment |
LAI Qi-wei1 LIU Qiang2 LEI Xing3 WANG Li-li4 JIANG Yun4 LU Cong1 HUANG Li-fang1 WEN Tai-pei5 |
1.Clinical Laboratory,the First People′s Hospital of Shaoguan City in Guangdong Province,Shaoguan 512000,China;
2.Department of Orthopedics,the First People′s Hospital of Shaoguan City in Guangdong Province,Shaoguan 512000, China;
3.Department of Dermatology,the First People′s Hospital of Shaoguan City in Guangdong Province,Shaoguan 512000,China;
4.Department of Gynecology and Obstetrics,the First People′s Hospital of Shaoguan City in Guangdong Province,Shaoguan 512000,China;
5.Department of E.N.T.,the First People′s Hospital of Shaoguan City in Guangdong Province,Shaoguan 512000,China |
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Abstract ObjectiveTo explore the calcitonin original determination application in patients with Syphilis diagnosis and treatment.MethodsFrom January 2015 to September 2016,151 patients with Syphilis(observation group)were given immunofluorescence chromatography,160 patients healthy subjects were sleeted at the same time as control group. The changes of serum procalcitonin PCT level was compared between the two groups.ResultsPCT in the observation group was(8.7±1.1)ng/ml and the control group was(0.3±0.1)ng/ml before the treatment,the difference was significant (t=96.182,P=0.000).The positive rate of PCT was 93.9%in the patients with stageⅠSyphilis in the observation group, the positive rate of PCT was 60.0%in the patients with stageⅡ Syphilis,the positive rate of PCT was 42.1%in the patients with stageⅢSyphilis,the positive rate of PCT was 20.0%in the patients with latent Syphilis,the positive rate of PCT was 90.9%in the patients with congenital Syphilis,and the positive rate of PCT was 84.6%in the patients with pregnancy Syphilis,there were significant differences(χ2=99.901,P=0.000).ConclusionThe application value of procalcitonin determination in the diagnosis and treatment of Syphilis is of great value,which can provide important information for the clinical diagnosis and treatment.
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[1] |
Schuetz P,Christ-Crain M,Thomann R,et al.Effect ofprocalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections;the Pro-HOSP randomized controlled trial[J].JAMA,2009,302(10):1059-1066
|
[2] |
Bouadma L,Luyt CE,Tubach F,et al.Use of procalcitonin to reduce patients exposure to antibiotics in intensive care units(PRORATA trial):a multicentre randornised controlled trial[J].Lancet,2010,375(9713):463-474.
|
[3] |
Christ-Crain M,Opal SM.Clinical review the of biomarkers in the diagnosis and management of community-acquired pneumonia[J].Crit Care,2010,14(1):203.
|
[4] |
降钙素原急诊临床应用专家共识组.降钙素原(PCT)急诊临床应用的专家共识[J].中华急诊医学杂志,2012,21(9):944-951.
|
[5] |
郑文亮,任丽娟.血液降钙素原与儿童败血症的相关性研究[J].检验医学与临床,2011,8(5):558-559.
|
[6] |
刘杰,迟小伟,汪运山.血清降钙素原、C-反应蛋白及白介素-6联合测定在鉴别细菌和病毒感染中的价值研究[J].医学检验与临床,2011,22(2):3-5.
|
[7] |
陈社安,李炜煊,麦爱芬,等.定量检测降钙素原在危重患者感染诊断及其预后判断中的临床价值[J].检验医学与临床,2011,8(4):416-417.
|
[8] |
王凯飞,沈定霞,刘朝军,等.血清降钙素原定量检测与血培养结果的比较[J].中华检验医学杂志,2012,35(3):243-246.
|
[9] |
胡可,刘思文,梁湘辉.降钙素原在细菌感染中临床应用的研究[J].中华医院感染学杂志,2011,21(1):30-33.
|
[10] |
熊玮平,代小英,黄立冠,等.血清降钙素原鉴别细菌感染的临床价值[J].检验医学与临床,2011,8(10):1192-1194.
|
[11] |
张文静.血清CRP、IL-6、PCT的检测在新生儿败血症中的诊断价值[J].国际检验医学杂志,2014,35(6):786-787.
|
[12] |
余建,邵强,王权,等.联合检测presepsin、降钙素原和C反应蛋白对脓毒症早期诊断及预后评估的价值[J].临床检验杂志,2014,37(3):200-203.
|
[13] |
丁爽,闫玲,李若倩,等.PCT和CRP对菌血症的诊断价值比较[J].国际检验医学杂志,2014,35(7):892-893.
|
[14] |
徐定华,石秋萍,王超,等.降钙素原在感染性疾病诊断中应用价值的临床病例分析[J].临床和实验医学杂志2014,13(8):679-681.
|
[15] |
朱旭利,余算,郑婷婷.梅毒患者C反应蛋白和血沉的测定[J].中国皮肤性病学杂志2014,28(2):163-164.
|
[16] |
谢健敏,卢解红,余一海.血清降钙素原对危重患者感染的预测价值[J].广东医学2013,34(2):264-266.
|
[17] |
高敏,李崇进,曾白华.降钙素原与C反应蛋白联合检测在成人下呼吸道感染中的临床价值[J].中国现代医生,2013,51(7):88-89.
|
[18] |
周卫,刘文丽,杨秋娥.血清降钙素原与C反应蛋白联合检测在新生儿感染性疾病中的应用[J].中医学报,2013,28(12):210.
|
[19] |
黄井堂.C反应蛋白在梅毒患者血清中的研究[J].中国卫生产业,2012,9(16):26-27.
|
[20] |
迟延芳.梅毒螺旋体阳性患者C反应蛋白的变化及意义[J].河北医学,2012,18(12):57-58
|
[21] |
严芝光.姚海东.二期梅毒患者治疗前后血清C-反应蛋白浓度变化比较[J].中国误诊学杂志,2010,10(18):212-213.
|
[22] |
刘婷,王亮,温贵华.隐性梅毒患者血生化指标的分析[J].国际检验医学杂志,2013,34(17):2294-2295.
|
[23] |
朱浩稳,周卫民,郭琪.500例梅毒患者血清抗核抗体和抗心磷脂抗体检测结果分析[J].检验医学与临床,2013,10(18):2410-2411.
|
|
|
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