Abstract：Objective To analyze the application effect of transcranial magnetic stimulation combined with antipsychotics in vagrant psychosis. Methods A total of 114 vagrant psychosis patients admitted to our hospital from June 2018 to May 2019 were selected as the research objects.According to the method of random number table method, they were divided into the control group (57 cases) and the observation group (57 cases).The control group was treated with Olanzapine, and the observation group was treated with Olanzapine and transcranial magnetic stimulation.The clinical efficacy, positive and negative symptom scale (PANSS), Pittsburgh sleep quality scale (PSQI), personal and social function scale (PSP) and adverse reactions were compared between the two groups. Results The total effective rate of the observation group was 75.44%, which was higher than that of the control group (56.14%), the difference was statistically significant (P＜0.05).There were no significant differences in PANSS score, PSQI score and PSP score between the two groups before treatment (P＞0.05).The PANSS and PSQI scores of the observation group after treatment were (57.62±3.91) and (5.08±1.92) points, which were lower than those of the control group ([76.54±3.15]and [8.67±2.04]points),the differences were statistically significant (P ＜0.05).The PSP score of the observation group after treatment was(63.46±7.05) points, which was higher than that of the control group ([50.89±6.21]points), the difference was statistically significant (P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05). Conclusion The combination of transcranial magnetic stimulation and antipsychotic drugs is safe and effective in the treatment of vagrant psychosis, which is beneficial to relieving mental symptoms and sleep disorders, and can restore social functions.
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