Abstract：Objective To analyze the effect of occupational recreational therapy and nursing intervention on sleep disorder and agitation behavior in patients with Alzheimer′s disease.Methods From April 2018 to January 2019,69 patients with Alzheimer′s disease were selected as the research subjects,and they were randomly divided into experimental group (35 cases) and control group (34 cases).The experimental group received occupational recreational therapy plus nursing intervention,and the control group received routine nursing.The scores of the mini-mental state examination (MMSE),Co-hen-Mansfield agitation inventory (CMAI),and Pittsburgh sleep quality index (PSQI) before and after nursing intervention were analyzed in the two groups,and the incidence of safety events was compared between the two groups.Results There was no significant difference in MMSE score between the two groups before nursing intervention(P＞0.05).The MMSE scores of patients in the experimental group after 8 and 16 weeks of nursing intervention were higher than those in the control group,and the differences were statistically significant (P＜0.05).There was no significant difference in CMAI score between the two groups before nursing intervention (P＞0.05).The CMAI scores of patients in the experimental group after 8 and 16 weeks of nursing intervention were lower than those in the control group,and the differences were statistically significant (P＜0.05).There was no significant difference in PSQI score between the two groups before nursing intervention (P＞0.05).The PSQI scores of patients in the experimental group after 8 and 16 weeks of nursing intervention were lower than those in the control group,and the differences were statistically significant (P＜0.05).The total incidence rate of safety events after nursing intervention in the experimental group was 0.00%,which was lower than the 11.76% in the control group,and the difference was statistically significant (P＜0.05).Conclusion The application of occupational recreational therapy and nursing intervention in patients with Alzheimer′s disease can not only improve the quality of sleep,but also avoid the occurrence of aggressive behavior,reduce the incidence of safety events and improve the life quality of patients,which has significant clinical value.
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