Evaluation of anti-inflammatory activity of different polar parts of Portulaca oleracea L.
CHEN Xin-jiang1* XIA Jia-yin2*
1.School of Medical Technology,Ningbo College of Health Sciences,Zhejiang Province,Ningbo 315100,China;2.School of Pharmaceutical Engineering,Zhejiang Pharmaceutical College,Zhejiang Province,Ningbo 315100,China
Abstract：Objective To compare the anti-inflammatory activity of different polar parts(water,ethanol,n-butyl alcohol,ethyl acetate,petroleum ether)extracts of Portulaca oleracea L..Methods Different polar parts extracts of Portulaca oleracea L.acted on mouse macrophage RAW264.7 cultured in vitro.MTT method was used to determine the cell vitality of the different extracts and Griess kit was used to measure the level of nitric oxide(NO)secreted by cells.Results Extracts of purslane water,n-butyl alcohol,ethyl acetate and petroleum ether could promote the proliferation of RAW264.7 macrophages.Extracts of ethanol,n-butanol,ethyl acetate,and petroleum ether could prevent macrophages induced by LPS from secreting NO.Conclusion Extracts of purslane ethanol,n-butanol,ethyl acetate and petroleum ether have potential anti-inflammatory activity.
陈新江;夏佳音. 马齿苋不同极性部位的抗炎活性评价[J]. 中国当代医药, 2018, 25(26): 8-12.
CHEN Xin-jiang;XIA Jia-yin. Evaluation of anti-inflammatory activity of different polar parts of Portulaca oleracea L.. 中国当代医药, 2018, 25(26): 8-12.
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