Abstract：Objective To investigate the effect of intracoronary injection of verapamil through restructured balloon catheter in the treatment of acute coronary syndrome (ACS).Methods A total of 90 ACS patients with no-reflow and slow flow who underwent percutaneous coronary intervention in our hospital from December 2015 to July 2017 were selected as the subjects.They were divided into control group and observation group by random number table method,with 45 cases in each group.In the control group,verapamil was injected into the coronary artery with a simple guiding catheter,and in the observation group,verapamil was injected through restructured balloon catheter.The grading of thrombolysis in myocardial infarction (TIMI)and changes of corrected TIMI frames were compared between the two groups,and the incidence of adverse cardiovascular events during hospital stay was also observed.Results The TIMI flow grading of the observation group was better than that of the control group.The number of corrected TIMI frames was less than that of the control group.The incidence of adverse cardiovascular events in the observation group(6.67%)was lower than that in the control group(31.11%),the difference was statistically significant(P<0.05).Conclusion Treatment of acute coronary syndrome characterized by no-reflow and slow flow with intracoronary injection of verapamil through restructured balloon catheter obtains a remarkable effect on improving coronary blood flow,reducing the occurrence of adverse cardiovascular events,and guaranteeing the own health status,which is worthy of clinical promotion.
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