Abstract:ObjectiveTo observe the clinical curative effect of observation of sublingual administration of Captopril curing emergency of hypertension.Methods Seventy-five patients with emergency of hypertension treated in emergency department of our hospital from July 2015 to December 2016 were selected.The subjects were divided into the control group(35 cases,Nitroglycerin Injection was used)and observation group(40 cases,sublingual administration of Captopril was added)according to the different wards for attending doctor.The antihypertensive effect of after 10,30,60 min treatment was evaluated,and the change of blood pressure index before treatment and after 10,30,60 min treatment were compared between the two groups.Results The clinical treatment rate of observation group after 10,30,60 min treatment was 32.5%,72.5%and 90.0%respectively while the control group was 20.6%,58.8%and 79.4%,and the treatment effect in the observation group was better than that in the control group(P<0.05).There was no significant difference in blood pressure between the two groups before medication(P>0.05).After 10,30,60 min treatment,SBP and DBP value in the observation group were lower than those in the control group(P<0.05).Conclusion Clinical effect observation of sublingual administration of Captopril curing emergency of hypertension is ideal,the improvement of blood pressure is good.