Abstract:Objective To investigate the significance of SPECT/CT99Tcmimaging in the assessment of residual thyroid tissue and the metastasis of differentiated thyroid carcinoma(DTC)before131I treatment.Methods 72 patients with DTC treated in our hospital from November 2013 to August 2016 were collected and treated with131I.Before the implementation of131I treatment,99TcmSPECT/CT thyroid static imaging was conducted,and the range included neck,chest, and fault fusion imaging was conducted routinely in neck and chest.After 5-8 days131I treatment,whole-body imaging (Rx-WBS)was conducted,and fault fusion imaging was conducted routinely in neck and chest,and other parts of the abnormal uptake foci was added with fault fusion imaging.Two kinds of imaging results were compared before and after treatment.Results99TcmSPECT/CT imaging and therapeutic dose of131I SPECT/CT imaging showed that the positive rate of residual thyroid was 90.3%(65/72),97.2%(70/72)respectively.The coincidence rate was 93.1%(67/72)between99TcmSPECT/CT imaging before treatment and131I99TcmSPECT/CT imaging after treatment.Among 72 patients with131I treatment,7 cases of therapeutic doses of131I SPECT/CT imaging for lymph node or lung metastasis and bone metastasis,and the corresponding parts of abnormal uptake lesions was found in 5 cases by99TcmSPECT/CT thyroid imaging.Transfer consistency was 71.4%(5/7)found.Conclusion99TcmSPECT/CT thyroid imaging conducted before131I treatment for differentiated thyroid carcinoma not only can well understand the residual thyroid,but also can find some metastatic lesions before treatment,and it has a very guidence significance for evaluation and development of therapeutic dose before treatment.
Verma N,Singh-Wadhwa S,Arvela OM.Metastatic thyroid cancer visualized on technetium pertechnetate and iodine-131 scintigraphy[J].Clin Nucl Med,2002,27(8):610.