Effect of Nifuratel and Three Vitamins and Nysfungin Suppositories on vaginal microflora disorder in pregnant women with mycotic vaginitis
LIU Mei-rong1CHI Zhi-qun2ZHANG Yan3
1.Department of Obstetrics and Gynecology,Ruijin Maternal and Child Health Care Hospital,Jiangxi Province,Ruijin 342500,China;
2.Department of Obstetrics and Gynecology,Ruijin People's Hospital,Jiangxi Province,Ruijin 342500,China;
3.Central Health Center of Zhaowuyang Town,Jiangxi Province,Ruijin 342500,China
Abstract：Objective To investigate the Effect of Nifuratel and Three Vitamins and Nysfungin Suppositories on vaginal microflora disorder in pregnant women with mycotic vaginitis.Methods Sixty patients with mycotic vaginitis during pregnancy admitted to the Department of Obstetrics and Gynecology,Maternal and Child Health Hospital of Ruijin city from January 2019 to December 2020 were retrospectively selected as the research subjects,and were divided into observation group(30 cases)and control group(30 cases)according to treatment methods.The control group was treated with Nifurtel Nystatin Vaginal Ointment,and the observation group was treated with Nifurtel Nystatin Vaginal Ointment combined with Three Vitamins and Nysfungin Suppositories.The clinical treatment effect,vaginal pH value,total incidence of adverse reactions,recurrence rate,colony≥1/2 area rate and correction rate of vaginal flora were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).The vaginal pH value of the observation group was lower than that of the control group,the disease recurrence rate of the observation group was lower than that of the control group,and the bacterial colony≥1/2 area rate and vaginal microflora correction rate of the observation group were higher than that of the control group,the differences were statistically significant(P<0.05).The total incidence of adverse drug reaction in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion in the treatment of mycotic vaginitis of pregnancy,the combination of Nifuratel and Three Vitamins and Nysfungin Suppositories can significantly improve the treatment effect,improve the vaginal environment,increase the area rate of beneficial flora in vagina,increase the correction rate of flora in vagina,improve the disorder of vaginal flora,and control the recurrence rate and adverse reactions,which is worthy of promotion.
刘美荣；池志群；张 燕. 硝呋太尔和三维制霉素栓治疗妊娠期霉菌性阴道炎患者阴道菌群紊乱的效果[J]. 中国当代医药, 2021, 28(32): 113-115.
LIU Mei-rong；CHI Zhi-qun；ZHANG Yan. Effect of Nifuratel and Three Vitamins and Nysfungin Suppositories on vaginal microflora disorder in pregnant women with mycotic vaginitis. 中国当代医药, 2021, 28(32): 113-115.
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