In recent years,the problem of drug safety has gradually become the focus of social attention.Scientific and standardized use of drug standards is particularly important to ensure drug safety.At present,there are many problems in drug standard management,such as many standards,difficult to query,delay in becoming a regular,multiple standards for one product and so on.The standard management system needs to be further improved.Based on the analysis of the problems existing in the management and implementation of drug quality standards,this paper puts forward the optimization measures of quality standard management in view of the related problems,and further ensures the safety and effectiveness of drugs and improves the work efficiency of functional departments with accurate standards and scientific management methods.