CT联合血清学指标在女性盆腔附件包块术前分期评估中的应用

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Abstract Objective To investigate the value of CT combined with serum carbohydrate protein 125(CA125)and human epididymal protein 4(HE4)in the preoperative staging of female pelvic adjunct mass.Methods A total of 92 female patients with pelvic accessory mass admitted to Jianli People′s Hospital in Hubei Province from September 2016 to September 2019 were selected as the research objects.All patients underwent CT examination,blood samples were collected to detect serum levels of CA125 and HE4,and pathological puncture diagnosis was performed to clarify the nature of the mass.The consistency between CT combined with serum CA125 and HE4 diagnosis and pathological diagnosis was analyzed to determine the sensitivity,specificity and accuracy of the combined diagnosis.With pathological staging as the gold standard,the evaluation value of CT combined with serum CA125 and HE4 for preoperative staging of female pelvic adjuncts was analyzed.Results Of the 92 patients,41(44.57%)were malignant and 51(55.43%)were benign.The levels of serum CA125 and HE4 in benign group were lower than those in malignant group,the differences were statistically significant(P<0.05).The consistency between CT diagnosis of pelvic adnexal malignant masses and pathological diagnosis was 0.732.The consistency of serum CA125 combined with HE4 in the diagnosis of pelvic adrenal malignancy was 0.594.The consistency of CT combined with serum CA125 and HE4 in the diagnosis of pelvic adnexal malignant masses was 0.801.With pathological puncture diagnosis as the gold standard,the total coincidence rate of CT combined with serum CA125 and HE4 in the evaluation of preoperative clinical staging of patients with malignant mass was 80.49%.The serum CA125 and HE4 of stage Ⅰpatients were lower than those of stage Ⅱand Ⅲ,and the serum CA125 and HE4 of stage Ⅱpatients were lower than that of stage Ⅲpatients,the differences were statistically significant(P<0.05).Conclusion CT combined with serum CA125 and HE4 has a high value in the identification of pelvic appendages including properties,and can be used in preoperative staging evaluation.

Key words： CT diagnosis Carbohydrate antigen 125 Human epididymal protein 4 Preoperative staging

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	ZHANG Yan

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ZHANG Yan. Application of CT combined with serological index in preoperative staging evaluation of female pelvic adjunct mass[J]. 中国当代医药, 2021, 28(25): 143-146.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I25/143

[1]	Maria FI，Esperanza BHA，Maria SFC.Pelvic cystic mass and ipsilateral renal agenesis detected by ultrasound in a young girl：early onset of herlyn-werner-wunderlich syndrome[J].Med Ultrason，2016，18（3）：405-406.
[2]	申晓俊，解骞，梁宗辉，等.女性盆腔肿物的影像诊断思维[J].影像诊断与介入放射学，2019，28（2）：154-156.
[3]	郭利清，杨舟.超声造影、CT、MRI 在卵巢肿瘤临床应用比较[J].中国CT 和MRI 杂志，2016，14（10）：92-95.
[4]	Muallem MZ，Parashkevova A，Almuheimid J，et al.Preoperative CA-125 values as a predictive factor for the postoperative outcome in primary serous ovarian cancer[J].Anticancer Res，2017，37（6）：3157-3161.
[5]	王雅贤，陈琼华.CA125，HE4，ROMA 及RMI 在附件包块诊断中的应用价值[J].中国实用妇科与产科杂志，2020，36（12）：40-44.
[6]	林林，鞠明秀，乔志伟，等.HE4，CA125 与ROMA 模型联合检测诊断卵巢上皮性癌价值研究[J].中国实用妇科与产科杂志，2019，35（12）：1384-1387.
[7]	童萌，孙立新.血清糖类抗原125 及人附睾蛋白4 联合检测对卵巢上皮性癌的诊断价值[J].肿瘤研究与临床，2019，31（10）：653-657.
[8]	李国芳.增强CT、超声联合检测对术前鉴别卵巢病变良恶性的价值及影像特点分析[J].中国CT 和MRI 杂志，2019，17（3）：109-112.
[9]	伍丽，黄健容，兰易，等.CEA、CA199 和CA125 单独和联合应用在卵巢癌诊断中的效能分析[J].中国妇产科临床杂志，2020，21（1）：56-57.
[10]	蔡新宇，肖蕾，梁晓平.超声及多层螺旋CT 鉴别女性盆腔囊性肿块病变的价值比较[J].中国CT 和MRI 杂志，2016，14（2）：106-108.
[11]	朱玉春，傅行礼，周伟，等.盆腔巨大囊实性肿块伴钙化——请分析病变性质[J].临床放射学杂志，2019，38（2）：375-376.
[12]	王海燕，杨宪鲁.疑似卵巢恶性肿瘤的巨大硬化性间质瘤一例[J].肿瘤研究与临床，2016，28（11）：775-776.
[13]	龚时鹏，陈咏宁，张雅迪，等.血清CA125 和HE4 水平及ROMA、CPH-I 模型在鉴别卵巢良恶性肿瘤中的价值对比[J].南方医科大学学报，2019，39（12）：1393-1401.
[14]	郭丽璇，胡琼英，付新刚，等.RDW 和CA125 联合应用对卵巢癌早期诊断的价值评价[J].现代预防医学，2020，47（6）：1079-1081，1090.
[15]	贺帅，马黎明，来艳君.HE4、CA125、SMRP 检测联合ROMA 在卵巢癌诊断中的应用[J].实用癌症杂志，2019，34（3）：18-20，24.
[16]	熊雯，周新娥，黄娟，等.血清CA125、HE4 及IL-17 检测对上皮性卵巢癌的早期诊断价值分析[J].中国计划生育和妇产科，2016，8（3）：69-73.
[17]	张志安，易红艳，左鹏，等.CT 和超声单项、联合检测诊断卵巢恶性肿瘤及术前临床分期的价值观察[J].中国CT 和MRI 杂志，2019，17（8）：114-116.
[18]	王恩力，白玫，周坤.64 排多层螺旋CT 与多普勒超声在女性盆腔囊性肿块病变诊断中的临床价值[J].中国妇幼保健，2019，34（20）：4823-4825.