生长激素促分泌素的临床研究进展

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Abstract Growth hormone secretagogue(GHS)is a generic term to describe compounds that increase growth hormone release.GHSs include agonists of the growth hormone secretagogue receptor,and agonists of the growth hormone-releasing hormone receptor.Several GHSs have been developed with a view to treating or diagnosing of growth hormone deficiency,which causes growth retardation,gastrointestinal dysfunction,and altered body composition,and in-depth studies on their mechanisms and pharmacology have been conducted.This review will focus on the history,pharmacological findings,and randomized clinical trial data of GHS.Furthermore,the author will highlight the publicly disclosed clinical trials regarding GHS.

Key words： Growth hormone secretagogue Anamorelin Gastrointestinal dysfunction Growth retardation

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	Articles by authors
	MENG Guang-peng
	LI Si-jun
	MA Hao-yu
	XU Miao
	LIU Shuang
	GAO Jian
	FU Xiao-ping
	ZHANG Lan

Cite this article:

MENG Guang-peng,LI Si-jun,MA Hao-yu, et al. Clinical research progress of growth hormone secretagogues[J]. 中国当代医药, 2021, 28(25): 41-47转55.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I25/41

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