人类脐带间充质干细胞的功能性与临床应用的研究进展

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Abstract Human umbilical cord mesenchymal stem cells(hUC-MSCs)as a kind of stem cells with great development potential,are easy to collect and do not involve ethics.hUC-MSCs can be collected from the perivascular tissues,arteries and veins of the umbilical cord and the part of Wharton jelly.Its proliferation and differentiation characteristics are remarkable,and it can promote tissue repair and immune regulation.The quantity and quality of hUC-MSCs from different individuals were different.hUC-MSCs have been applied more and more widely in the field of cell therapy,and have achieved remarkable clinical effects in the fields of organ injury disease,nervous system disease,endocrine system disease and so on.This paper reviews the research progress in the function,safety and clinical application of umbilical cord mesenchymal stem cells,summarizes their therapeutic value and the problems faced in the research process,in order to explore more application potential of hUC-MSCs.

Key words： Human umbilical cord Mesenchymal stem cells Directional differentiation Immunoregulation Transplant Cell therapy

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	Articles by authors
	ZHANG Xue-juan
	SUN Xu-yan
	YANG Wei-juan
	ZHANG Xiu-tao
	GAO Zong-sheng
	SUN Hong-tao

Cite this article:

ZHANG Xue-juan,SUN Xu-yan,YANG Wei-juan, et al. Research progress in functional and clinical applications of human umbilical cord mesenchymal stem cells[J]. 中国当代医药, 2021, 28(27): 39-43.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I27/39

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