香菇多糖治疗胃癌患者的临床效果

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Abstract Objective To explore the Clinical effect of Lentinan in the treatment of patients with gastric cancer.Methods A total of 150 patients with gastric cancer who were admitted to Yancheng No.1 People′s Hospital from January to December 2019 were selected as the research subjects.According to the random number table method, they were divided into control group and study group, with 75 cases in each group.The control group was treated with chemotherapy,and the study group was treated with Lentinan on the basis of the control group.The immune function and clinical efficacy before and after treatment as well as the adverse reactions and quality of life caused by chemotherapy were compared between the two groups.Results After treatment, the indexes of CD3+, CD4+, CD4+/CD8+, natural killer (NK)cells, immunoglobulin A (IgA), immunoglobulin G (IgG), and immunoglobulin M (IgM) in the study group were higher than those of the control group, while the index of CD8+ was lower than that of the control group, the differences were statistically significant (P＜0.05).After treatment, there was no significant difference in the incidence of abnormal liver function between the two groups (P＞0.05).The incidence of leukopenia, gastrointestinal reaction and platelet decline in the study group were lower than those in the control group, and the improvement rate of quality of life was higher than that in the control group, the differences were statistically significant (P＜0.05).The effective rate of the study group was higher than that of the control group, and the difference was statistically significant (P＜0.05).Conclusion Lentinan has high therapeutic value in patients with gastric cancer, which is worthy of clinical application.

Key words： Lentinan Gastric cancer Quality of life Immune function Adverse reactions

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	LI Hai-bo
	SONG Yan

Cite this article:

LI Hai-bo,SONG Yan. Clinical effect of Lentinan in the treatment of patients with gastric cancer[J]. 中国当代医药, 2021, 28(10): 183-186.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I10/183

[1]	梅丽红.早期胃癌的临床病理特点与内镜下的表现分析[J].中国内镜杂志，2018，24（2）：81-85.
[2]	檀建平，张军，赵羽，等.复方斑蝥胶囊联合FOLFOX6 方案对晚期胃癌患者无进展生存期的影响[J].中国地方病防治杂志，2018，33（3）：353-355.
[3]	中华人民共和国卫生部医政司.中国常见恶性肿瘤诊治规范[S].2 版.北京：北京医科大学中国协和医科大学联合出版社，1991：2-3.
[4]	周新东.香菇多糖联合化疗治疗肺癌近期疗效和免疫功能的评估[J].中国急救医学，2018，38（1）：297-298.
[5]	王启船，王青，屈中玉，等.香菇多糖联合化疗对老年胃癌患者血清IL-2、IL-6 及免疫功能的影响[J].中国老年学杂志，2018，46（7）：1609-1612.
[6]	毛光华，王军，贾林梓，等.脾多肽辅助FOLFOX 化疗治疗晚期胃癌的效果及对患者生存质量、免疫功能的影响[J].山东医药，2019，59（11）：78-80.
[7]	汪丹丹，郑蔚，侯守超，等.胃癌患者化疗期间症状群与生活质量相关性的纵向研究[J].中国全科医学，2019，22（3）：47-54.
[8]	黄孟欣，胡玲，张云展，等.中药注射剂联合FOLFOX4 化疗方案治疗胃癌的贝叶斯网状meta 分析[J].中药药理与临床，2019，35（1）：162-166.
[9]	林柳兵，李毅平，阙任烨，等.胃癌术后及化疗后的中医饮食调养[J].辽宁中医杂志，2019，46（3）：501-503.
[10]	芮雯，游思远，吴小清，等.香菇多糖对人结直肠癌上皮细胞SW837 免疫原性死亡相关分子表达的影响[J].中国免疫学杂志，2019，35（8）：58-62.
[11]	苏畅，李小江，贾英杰，等.香菇多糖的抗肿瘤作用机制研究进展[J].中草药，2019，50（6）：1499-1504.
[12]	王海霞.香菇多糖在老年乳腺癌化疗中的辅助效果及对外周血炎症因子和肿瘤浸润的影响[J].中国老年学杂志，2018，38（10）：2369-2371.
[13]	万茜淋，任雨贺，刘淑莹.香菇多糖的药理活性研究进展[J].中国药房，2018，846（8）：1140-1144.
[14]	许涛，景红霞，李林均，等.调强放疗联合替吉奥同步化疗及DC-CIK 治疗不能手术的局部进展期老年胃癌患者的临床疗效[J].中国老年学，2018，38（19）：4635-4638.
[15]	徐丹兵，陈宏才，郏丽萍，等.氟比洛芬酯注射液联合地佐辛注射液用于胃癌根治术患者镇痛的临床研究[J].中国临床药理学杂志，2018，34（17）：2070-2072.
[16]	乔金翰，刘德华，王少雷，等.经动脉灌注化学治疗中晚期胃癌的临床效果[J].中国介入影像与治疗学，2020，17（4）：198-201.
[17]	王达，潘春球，韩述岭，等.香菇多糖注射液提高胃肠癌化疗患者生存质量的临床研究[J].实用医学杂志，2012，28（24）：4143-4145.