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Study on the correlation between the changes of waistline and two kinds of immobilization methods in cervical cancer radiotherapy |
ZHONG Jia-jian QIU Min-min LIN Ze-huang HUANG Tai-ming MIN Meng-zhen XIAO Zhen-hua DENG Yong-jin |
Department of Radiotherapy, the First Affiliated Hospital, Sun Yat-sen University, Guangdong Province, Guangzhou 510080, China |
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Abstract Objective To explore the correlation between the changes of waistline and set-up errors of two kinds of immobilization methods in cervical cancer radiotherapy.Methods A total of 60 patients with cervical cancer who received radiotherapy in the First Affiliated Hospital, Sun Yat-sen University from June to December 2019 were retrospectively selected and divided into group A and group B according to the supine or prone position, with 30 cases in each group.Cone beam CT (CBCT) was performed once a week.The set-up errors of translation, rotation and waistline were recorded offline, and the correlation between the changes of waistline and set-up errors were calculated.Results The translation errors of X, Y and Z directions in group A were (-0.5±2.7), (-0.1±3.2), (-0.4±2.5) mm, and (-0.2±3.0),(-0.2±4.0), (2.0±4.1) mm in group B; the rotation errors of Rx, Ry and Rz in group A were (-0.6±2.2), (-0.2±0.8), (0.1±0.8)°, and (0.5±2.3), (-0.2±1.3), (0.5±0.9)° in group B.In Z, Rx and Rz directions, the difference between two groups was statistically significant (P<0.05).The change of waistline △C in group A and B was (-2.3±2.7) and (-1.4±2.0) cm respectively, the difference between two groups was statistically significant (P<0.05).There was a negative correlation between error of Z direction in group B and change of waistline △C (r=-0.618, P<0.05).Conclusion In the supine position of cervical cancer radiotherapy, the repeatability is better, but the change of waistline will lead to serious adverse reactions.In the prone position, the protection of small bowel is better, but the change of waistline has a greater impact on the accuracy of Z direction.In clinic, the change of waistline should be paid attention and intervention of bladder filling and weight should be taken if necessary.
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