|
|
|
| Effect of integrated traditional Chinese and Western medicine in the treatment of diabetic foot infection and its influence on serum inflammatory factors |
| LI Wei YANG Cai-yun |
| Department of Internal Medicine, Nanchang Hongdu Hospital of Traditional Chinese Medicine |
|
|
|
|
Abstract Objective To explore the effect of integrated traditional Chinese and Western medicine in the treatment of diabetic foot infection and its influence on serum inflammatory factors. Methods A total of 178 patients with diabetic foot infection admitted to Nanchang Hongdu Hospital of Traditional Chinese Medicine from February 2018 to March 2020 were selected as the research subjects,and they were divided into the control group(n=89)and the observation group(n=89) by the random number table method. The control group was treated with Western medicine, and the observation group was treated with integrated traditional Chinese and Western medicine. After 1 month of treatment, the treatment effect of patients was evaluated. The postoperative recovery time, traditional Chinese medicine syndrome scale score,dorsal foot artery diameter, blood flow velocity, vascular cell adhesion molecule 1 (VCAM-1), interleukin 6 (IL-6), tumor necrosis factor-α (TNF-α) and C-reactive protein (CRP) levels before and after treatment were compared between the two groups. Results After treatment, the time of granulation tissue growth, foot ulcer debridement and epithelial tissue formation in the observation group were faster than those in the control group, the differences were statistically significant (P<0.05). There were no significant differences in the score of traditional Chinese medicine syndrome scale,dorsal foot artery diameter and blood flow velocity between the two groups before treatment (P>0.05). After treatment,the scores of traditional Chinese medicine syndrome scale and blood flow velocity of the two groups were lower than those before treatment, and the dorsal foot artery diameter was increased compared with that before treatment, the differences were statistically significant (P<0.05). After treatment, the score of traditional Chinese medicine syndrome scale and the blood flow velocity of the observation group were lower than those of the control group, and the diameter of the dorsal foot artery was higher than that of the control group, the differences were statistically significant (P<0.05).Before treatment, there were no significant differences in serum inflammatory factor levels between the two groups (P>0.05). The levels of serum inflammatory factors in the two groups after treatment were lower than those before treatment,and the differences were statistically significant (P<0.01). The levels of serum inflammatory factors in the observation group after treatment were lower than those in the control group, and the differences were statistically significant (P<0.01). Conclusion The combination of traditional Chinese and Western medicine is effective in treating diabetic foot infection. It can promote the rehabilitation of the patients′ limbs, relieve the symptoms, improve the diameter of the dorsal artery of the foot, speed up blood flow, and significantly reduce the level of inflammatory factors in the patients,thereby promoting the recovery of inflammation. It is of great significance to the treatment of diabetic foot infection, and it is worthy of promotion and applicatio
|
|
|
|
|
|
| [1] |
焦鹏，吉书红.温阳活血汤联合穴位注射治疗糖尿病足（瘀血阻络）及对血清炎性因子的影响[J].世界中西医结合杂志，2019，14（9）：1271-1274，1278.
|
| [2] |
李明锐.沙格雷酯对糖尿病足病人血清胆红素及炎症因子水平的影响[J].蚌埠医学院学报，2018，43（7）：861-863，867.
|
| [3] |
崔俊芳，任荣.高压氧联合西洛他唑治疗糖尿病足患者的疗效及对血清胰岛素样生长因子1 的影响[J].中华航海医学与高气压医学杂志，2019，26（2）：116-119.
|
| [4] |
中国糖尿病足细胞与介入治疗技术联盟.糖尿病足介入综合诊治临床指南（第4 版）[J].中国介入影像与治疗学，2018，15（1）：3-12.
|
| [5] |
金晓明，韩思佳，吴雁翔.银离子敷料联合水凝胶治疗糖尿病足的效果及对相关血清炎症因子的影响[J].河北医科大学学报，2018，39（12）：1380-1383，1388.
|
| [6] |
蔡春沉，贾红卫，王肃.糖尿病足感染患者血清炎性因子水平与感染的相关性分析[J].中华医院感染学杂志，2019，29（6）：876-879.
|
| [7] |
薛俊，曹敏，张亮.高压氧对糖尿病足伴周围神经病变患者的疗效及对其相关血清指标和生活质量的影响[J].中华航海医学与高气压医学杂志，2018，25（5）：301-304.
|
| [8] |
刘刚，赵玉，李芳菲.胰岛素泵强化治疗2 型糖尿病足溃疡愈合的临床效果及对血清同型半胱氨酸和基质金属蛋白酶水平的影响[J].中国医师杂志，2020，22（5）：752-755.
|
| [9] |
王士朋，李春雷.中西医结合治疗急性痛风性关节炎及其对炎性因子的影响[J].长春中医药大学学报，2018，34（4）：137-140.
|
| [10] |
王利民.中西医结合治疗急性心力衰竭的疗效及对血清神经激素因子的影响[J].中西医结合心脑血管病杂志，2019，17（1）：103-105.
|
| [11] |
曹颖，王春梅，傅强.参麦注射液对感染性休克患者血流动力学及血清炎症因子的影响[J].中国中西医结合急救杂志，2019，22（1）：38-40.
|
| [12] |
王琼，朱晗婷，吴国荣，等.中西医结合治疗溃疡性结肠炎的疗效及对凝血和炎性因子水平的影响[J].海南医学院学报，2019，25（1）：5-8.
|
| [13] |
高速，田雪，姜维娜，等.中西医结合治疗2 型糖尿病合并冠心病的临床疗效及对血清成纤维细胞生长因子-21、Ghrelin 的影响与意义[J].海南医学院学报，2018，24（22）：17-21.
|
| [14] |
赵江蓉，杨沁彤，李苗华，等.三黄消炎方对糖尿病足感染湿热毒盛证患者肠道屏障及炎性反应的影响[J].中华中医药杂志，2018，33（6）：2696-2698.
|
| [15] |
闫程程，鞠上，曹欣，等.复方黄柏液负压滴灌治疗对糖尿病足感染创面及相关炎性因子的影响[J].中华糖尿病杂志，2018，34（7）：460-464.
|
|
|
|
