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| Research progress of intrapartum fever caused by epidural labor analgesia |
| WANG Yu YAN Yu-rong▲
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| Department of Anesthesiology,Binzhou Medical University Hospital,Shandong Province,Binzhou 256600,China |
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Abstract With the popularization of epidural analgesia technology and the increasing demand for parturients for reducing labor pain,more and more medical institutions have carried out labor analgesia.However,the adverse outcomes of maternal and infant caused by epidural related maternal fever (ERMF) have perplexed countless medical workers.The underlying pathophysiological processes of intrapartum fever remain elusive.It may be related to aseptic inflammatory reaction mediated by proinflammatory cytokines,the imbalance of maternal thermoregulation,the effect of local anesthetics,epidural puncture trauma and so on.Intrapartum fever may increase obstetric interventions,increase the rate of cesarean section,assist vaginal deliveries,and the use of antibiotics.It may affect the neonatal nervous system and increase neonatal antibiotic exposure.Therefore,a more comprehensive understanding of the etiology and harm of ERMF is conducive to taking effective measures to reduce its incidence and allow a better outcome of both mothers and infants.
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