经鼻高流量氧疗对支气管哮喘急性发作的疗效

Abstract
Figure/Table
References (20)
Related Citation (15)

Download: PDF (0 KB) HTML (35 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the efficacy of nasal high-flow oxygen therapy on acute exacerbation of bronchial asthma and its effect on prognosis. Methods A total of 64 patients with acute bronchial asthma and respiratory failure who were admitted to Jingzhou Chest Hospital, Hubei Province from Janurary 2018 to August 2019 were selected as the research subjects. According to random number table method, they were divided into observation group (n=32) and control group (n=32). The observation group received nasal high-flow oxygen therapy and the control group received conventional oxygen therapy, the differences in lung function, efficacy, and prognostic indexes between the two groups after treatment were compared. Results The observation group patients′ forced expiratory volume in one second, forced vital capacity and peak expiratory flow after treatment were higher than those in the control group, the differences were statistically significant (P<0.05). The total effective rate of the observation group (93.75%) was higher than that of the control group (81.25%), the difference was statistically significant (P<0.05). The number of acute attacks and the number of hospitalizations in the observation group were fewer than those in the control group, and the length of hospital stay was shorter than that of the control group, the differences were statistically significant (P<0.05). Conclusion Assisted transnasal high-flow oxygen therapy can improve lung function indexes of patients with acute bronchial asthma complicated by respiratory failure, shorten hospital stay and improve treatment effect, which is worthy of clinical promotion and application.

Key words： Nasal high-flow oxygen therapy Bronchial asthma Acute attack Effect Prognosis

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	NI Ying

Cite this article:

NI Ying. Efficacy of transnasal high flow oxygen therapy on acute attack of bronchial asthma[J]. 中国当代医药, 2021, 28(3): 55-61.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I3/55

[1]	季婵婵，宋爱琴，郑念举，等．加热、湿化经鼻高流量氧疗在中重度毛细支气管炎婴幼儿中的应用[J]．中华实用儿科临床杂志，2017，32（18）：1415．
[2]	杨圣强．经鼻高流量氧疗对慢性阻塞性肺疾病急性加重患者膈肌功能的影响：一项前瞻性随机对照研究[J]．中华危重病急救医学，2019，31（5）：551-555．
[3]	潘红，黄琴红，蔡英华，等．经鼻高流量氧疗在肺移植患者围术期的应用[J]．中国实用护理杂志，2018，34（4）：270-273．
[4]	Ou X，Hua Y，Liu J，et al.Effect of high-flow nasal cannula oxygen therapy in adults with acute hypoxemic respiratory failure：a meta-analysis of randomized controlled trials[J]．CMAJ，2017，189（7）：E260-E267．
[5]	中华医学会呼吸病学分会哮喘学组．支气管哮喘防治指南（2016年版）[J]．中华结核和呼吸杂志，2016，39（9）：675-697．
[6]	吕姗，安友仲．主动温湿化的经鼻高流量氧疗在成人患者中的应用[J]．中华危重病急救医学，2016，28（1）：84-88．
[8]	卢骁，高玉芝，吴春双，等．经鼻高流量氧疗在基于肺超声评估的高风险脱机患者中的应用[J].中华急诊医学杂志，2018，27（4）：367-372．
[9]	王丽娟，夏金根，杨晓军．成人经鼻高流量氧气湿化治疗的应用进展[J]．中华结核和呼吸杂志，2016，39（2）：153-157．
[11]	耿晓娟．经鼻高流量吸氧用于体外循环术后患者疗效观察[J]．国际麻醉学与复苏杂志，2018，39（8）：736-740．
[12]	沈佳伟，安友仲．拔除气管导管后患者的经鼻高流量吸氧治疗[J]．中华危重病急救医学，2017，29（1）：85-89．
[7]	Makdee O，Monsomboon A，Surabenjawong U，et al．High-flow nasal cannula versus conventional oxygen therapy in emergency department patients with cardiogenic pulmonary edema：A randomized controlled trial[J]．Ann Emerg Med，2017，70（4）： 465-472．
[10]	Zhong Y，Guo Y，Liu X，et al．Serum glycopatterns as novel potential biomarkers for diagnosis of acute-on-chronic hepatitis B liver failure[J]．Sci Rep，2017，6（7）：45 957．
[13]	Frat JP，Coudroy R，Marjanovic N，et al．High-flow nasal oxygen therapy and noninvasive ventilation in the management of acute hypoxemic respiratory failure[J]．Ann Transl Med，2017，5（14）：297．
[14]	李同林，刘蔺，周航．孟鲁司特钠片联合布地奈德福莫特罗对支气管哮喘患者临床预后及生化指标的影响分析[J]．中国地方病防治杂志，2017，（12）：1408-1409.
[15]	Zhao H，Wang H，Sun F，et al．High-flow nasal cannula oxygen therapy is superior to conventional oxygen therapy but not to noninvasive mechanical ventilation on intubation rate：a systematic review and meta-analysis[J]．Crit Care，2017，21（1）：184．
[16]	Xiu Wu，Wei Cao，Bin Zhang，et al.Effect of high-flow nasal cannula oxygen therapy vs conventional oxygen therapy on adult postcardiothoracic operation：A meta-analysis[J].Medicine，2018，97（41）：e12783.
[17]	Kim ES，Lee H，Kim S J，et al．Effectiveness of high-flow nasal cannula oxygen therapy for acute respiratory failure with hypercapnia[J]．J Thorac Dis，2018，10（2）：882-888.
[18]	Kubo T，Nakajima H，Shimoda R，et al．Noise exposure from high-flow nasal cannula oxygen therapy：A bench study on noise reduction[J].Respir Care，2018，63（3）：267-273．
[19]	Ricard JD，Dib F，Esposito-Farese M，et al．Comparison of high flow nasal cannula oxygen and conventional oxygen therapy on ventilatory support duration during acute-onchronic respiratory failure：study protocol of a multicentre，randomised，controlled trial.The HIGH-FLOW ACRF study[J].BMJ Open，2018，8（9）：e022983．
[20]	Zochios V，Collier T，Blaudszun G，et al．The effect of highflow nasal oxygen on hospital length of stay in cardiac surgical patients at high risk for respiratory complications：a randomised controlled trial[J]．Anaesthesia，2018，73（12）：1478-1488．