透明质酸钠宫腔注入联合雌孕激素序贯预防或治疗清宫术后宫腔粘连的临床效果

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Abstract ObjectiveTo investigate the clinical effect of sodium hyaluronate injection combined with estrogen and progesterone in the prevention and treatment of intrauterine adhesions after curettage.MethodsFrom January 2016 to March 2017,200 cases of artificial abortion and missed abortion in our hospital who had at least 2 times in the history of artificial abortion were selected as the research objects,they were divided into the control group and the observation group by taking computer random number method,100 cases in each group.The control group had not taken special treatment after the operation,the observation group had taken intrauterine injection of Sodium Hyaluronate combined with oral Estrogen and Progesterone after the operation.The amount of bleeding of intrauterine adhesions,the incidence of postoperative bleeding duration,duration of abdominal pain,menses time,reduce menstruation rate and amenorrhea rate were compared between two groups.ResultsThe adhesion of uterine cavity in the observation group were significantly lower than the control group,the difference was statistically significant(P＜0.05);the amount of bleeding in the observation group was less than that in the control group,the duration of bleeding,the duration of abdominal pain,the time of menstruation and tidal repetition were shorter than those in the control group,the differences were statistically significant(P＜0.05);3 months after surgery,the observation group of reduced rate of menstruation,the rate of closed were lower than the control group,the differences were statistically significant(P＜0.05).ConclusionThe combined Estrogen and Progesterone treated by sequential injection of Sodium Hyaluronate in uterine cavity repeatedly in patients with artificial abortion and missed abortion after curettage can effectively prevent postoperative intrauterine adhesions,but also can effectively relieve postoperative bleeding,abdominal pain and other symptoms,promote the recovery of patients after menstruation.

Key words： Artificial abortion Intrauterine adhesions Sodium Hyaluronate

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	Articles by authors
	ZHANG Jin-xian
	LIN Hui-ping
	LIU Hua-liu
	CHEN Yue-qiong

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ZHANG Jin-xian,LIN Hui-ping,LIU Hua-liu, et al. The clinical effect of Sodium Hyaluronate injection combined with Estrogen and Progesterone in the prevention and treatment of intrauterine adhesions after curettage[J]. 中国当代医药, 2017, 24(29): 68-70.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I29/68

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