红细胞分布宽度与原发性高血压患者血压变异性的相关性分析

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Abstract Objective To analyze the correlation of red blood distribution width (RDW) levels with blood pressure variability (BPV) in patients with primary hypertension.Methods Retrospective analysis was made on the clinical data of 220 patients with essential in Beijing Xicheng District Pingan Hospital from October 2017 to June 2019.24 hours ambulatory blood pressure monitoring was conducted.Plasma levels of RDW, fasting blood glucose and lipids were also examined.Patients were divided into 4 groups based on their RDW levels: group Ⅰwith 58 cases (RDW＜12.4%),group Ⅱwith 56 cases (12.4%≤RDW＜12.9%), group Ⅲwith 52 cases (12.9%≤RDW＜13.5%), group Ⅳwith 54 cases (RDW≥13.5%).In this study, the standard deviation of 2-hour ambulatory blood pressure reading was used as the index of BPV, including 24 hours systolic blood pressure standard deviation (24 h SSD), 24 hours diastolic blood pressure standard deviation (24 h DSD).The BPV of patients with different RDW levels was compared and the correlation between RDW and BPV was analyzed.Results Comparison of BPV indicators showed that the levels of 24 h SSD and 24 h DSD of group Ⅳwere higher than those of the group Ⅲ, the levels of 24 h SSD and 24 h DSD of groupⅢwere higher than those of the group Ⅱ, and the levels of 24 h SSD and 24 h DSD of group Ⅱwere higher than those of the group Ⅰ, and the differences were statistically significant (P＜0.05).The result of Pearson correlation analysis showed that RDW was positively correlated with 24 hours SSD and 24 hours DSD (r=0.727 and 0.557, P＜0.05).Conclusion The RDW level of patients with essential hypertension is positively correlated with BPV, RDW is closely related to BPV in patients with essential hypertension.

Key words： Primary hypertension Blood pressure variability Red blood distribution width Correlation

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	LIU Jian-feng
	ZHOU Zhi-min
	GAO Chao-ming
	WU Yi

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LIU Jian-feng,ZHOU Zhi-min,GAO Chao-ming, et al. Correlation analysis of red blood distribution width levels with blood pressure variability in patients with prim-ary hypertension[J]. 中国当代医药, 2021, 28(8): 59-61转65.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I8/59

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