沙库巴曲缬沙坦在高血压中的应用

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Abstract Hypertension is the most common cardiovascular disease in China.At present,the control rate of hypertension in China is very low.Long-term poorly controlled hypertension will cause serious complications in target organs such as heart,brain and kidney.In recent years,the activation of renin-angiotensin-aldosterone system (RAAS)and natriuretic peptide(NP)system has attracted increasing attention.As the only angiotensin-enkephalase inhibitor,Sacubitril/Valsartan can act on both the RAAS system and the NP system,and can be used as a new choice for patients with hypertension.In this paper,the advantages of Sacubitril/Valsartan in the treatment of hypertension were summarized by reviewing the clinical studies of Sacubitril/Valsartan in the treatment of hypertension.

Key words： Sacubitril/Valsartan Isolated systolic hypertension Salt sensitive hypertension Chronic kindney disease Obesity Heart failure

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	WANG Jun
	ZHANG Jing
	GONG Hang-yu

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WANG Jun,ZHANG Jing,GONG Hang-yu. Application of Sacubitril/Valsartan in hypertension[J]. 中国当代医药, 2021, 28(6): 26-29转34.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I6/26

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