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Infection rate of group B hemolytic streptococcus in middle and late pregnant women and its effect on maternal and fetal outcomes |
DU Cai-rong1 HU Jin2 LUO Jian-ting2 |
1.Clinical Laboratory,Guangzhou Baiyun District People′s Hospital,Guangdong Provinec,Guangzhou 510080,China;
2.Department of Obstetrics and Gynecology,Guangzhou Baiyun District People′s Hospital,Guangdong Provinec,Guangzhou 510080,China |
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Abstract Objective To investigate the infection risk of group B hemolytic streptococcus in middle and late pregnant women and its effect on the maternal and fetal outcomes.Methods By a random simple sampling,217 women in the middle and late pregnancyfor regular pregnancy tests were enrolled from March to December in 2017 in the department of obstetrics and gynecology in our hospital.The colloidal gold chromatography was used for group B hemolytic streptococcus detection,and the infection rate of group B hemolytic streptococcus was analyzed.After that,22 pregnant women with positive group B hemolytic streptococcus infection were enrolled as observation group,and the remaining 195 pregnant women with negative group B hemolytic streptococcus infection were as control group.The infection rate of group B hemolytic streptococcus,pregnancy outcomes including incidence of premature rupture of membranes,premature delivery,and fetal distress,and neonatal outcomes including incidence of neonatal infection,premature infant,and neonatal asphyxia in the two groups were compared.Results Twenty-two of the 217 patients were infected with group B hemolytic streptococcus,accounting for 10.1%.The infection rate of group B hemolytic streptococcus in≥30-year-old pregnant women was significantly higher than that in pregnant women less than 30 years old,and the difference was statistically significant(P<0.05).The incidence of premature rupture of membranes,premature delivery and fetal distress in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of neonatal infection in the observation group was higher than that in the control group,and the incidence of neonatal jaundice,premature infant and neonatal asphyxia were lower than those in the control group,with statistically significant differences(P<0.05).Conclusion Infection of group B hemolytic streptococcus in middle and late pregnant women can lead to adverse pregnancy outcomes such as premature delivery,premature rupture of membranes,and neonatal infection.It is necessary to standardize treatment interventions to improve pregnancy outcomes.
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