人工肝血浆置换术治疗肝衰竭的临床效果

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Abstract Objective To explore the clinical effect of artificial liver plasma exchange in the treatment of liver failure.Methods A total of 88 patients with liver failure who were admitted to the hospital fron March 2013and March 2019 were selected as the subjects.They were divided into group A(44cases)and group B(44cases)by the random number tablemethod.Groups A was given comprehensivemedical treatment,and group B were additionally treated with artificial liver plasma exchange on the basis of group A.The clinical effect,levels of liver function indicators and inflammatory factorswere compared between the two groups.Results After 2weeks of treatment,the improvement rate in group B was 75.00%,which was higher than that in group A (40.90%),the difference was statistically significant(P＜0.05).After treatment,the levels of serum aspartate aminotransferase (AST),alanine aminotransferase (ALT),total bilirubin(TBil),and serum interleukin (IL)-17,IL-12,and IL-35in group B were lower than those in group A,the differences were statistically significant(P＜0.05).Conclusion The effect of artificial liver plasma exchange is significant in the treatment of liver failure.It can effectively improve the liver function of patients and relieve inflammatory response.

Key words： Artificial liver plasma exchange Comprehensive medical treatment Liver failure Curative effect Inflammatory factor

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	Articles by authors
	LI Qing-qi
	GUO Ting
	ZHANG Li-li
	WANG Wei-xin

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LI Qing-qi,GUO Ting,ZHANG Li-li, et al. Clinical effect of artificial liver plasma exchange in the treatment of liver failure[J]. 中国当代医药, 2020, 27(17): 40-42.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I17/40

[1]	周芸.无肝素人工肝血浆置换术治疗肝功能衰竭的临床观察及护理[J].实用临床医药杂志，2017，21（8）：46-48.
[2]	周健，王笑笑，连江山，等.人工肝血浆透析滤过与选择性血浆置换联合连续性血液滤过治疗中晚期肝衰竭疗效及安全性比较[J].中华临床感染病杂志，2018，11（5）：369-371.
[3]	李刚磊，武杰，王世明.人工肝血浆置换治疗肝衰竭患者的疗效（72例）[J].医疗装备，2018，31（7）：8-9.
[4]	王艳红，朱翔，冯定云，等.人工肝支持慢加急性肝衰竭合并Ⅲ～Ⅳ期肝性脑病患者成功完成肝移植14例分析[J].中华肝脏病杂志，2018，26（9）：676-679.
[5]	严丽军，徐立新.人工肝选择性血浆置换治疗慢加亚急性肝衰竭及费效比分析[J].肝脏，2018，23（4）：361-362.
[6]	后金，黄娅，杨赋婕，等.人工肝血浆置换联合血浆灌流治疗35例肝衰竭效果观察[J].中外医学研究，2017，15（21）：1523-1525.
[7]	张凤丹.应用人工血浆置换机的人工肝血浆置换术在重度病毒性肝炎患者中的临床观察[J].中国医疗器械信息，2018，24（11）：568-569.
[8]	周宪伟，房忠卫.血浆凝血酶原活动度和血清甲胎蛋白、前白蛋白联合检测在人工肝血浆置换治疗重型肝炎的临床意义[J].中国医师进修杂志，2017，40（9）：773-776.
[9]	杨黎冰，仝静，祖晓满，等.血浆置换治疗乙肝相关性肝衰竭的疗效分析[J].临床消化病杂志，2017，29（6）：342-345.
[10]	雷鹏，段军民.人工肝少量血浆置换+胆红素吸附在重型肝炎肝衰竭中的应用[J].航空航天医学杂志，2017，28（4）：1236-1238.
[11]	万克强，田文广，苏畅.血浆置换联合连续性血液滤过治疗肝衰竭前期临床分析[J].重庆医科大学学报，2018，42（1）：52-55.
[12]	杨荣利，周恒杰.人工肝技术的研究进展[J].华西医学，2018，33（7）：652-654.
[13]	何小凤，罗玲，袁春兰，等.两种人工肝方法治疗重型乙型肝炎的近期疗效对比分析[J].重庆医学，2017，46（18）：2475-2477.
[14]	唐碧波，戴丽星，胡东辉，等.血浆置换与血浆灌流联合治疗肝衰竭的疗效及对炎症因子及肝功能的影响[J].现代生物医学进展，2017，17（25）：114-117.
[15]	徐晖，潘成，何雪明，等.血浆置换对肝衰竭患者血清炎症因子表达的影响[J].中外医学研究，2018，16（10）：11-13.