Clinical effect of whole-lung lavage in the treatment of pneumoconiosis
MAI Zi-jian1 YUAN Li-ling2 LIU Yang1
1. Department of Thoracic Surgery, the No.12 People′s Hospital of Guangzhou City Affiliated to Guangzhou Medical University,Guangdong Province,Guangzhou 510000,China；
2.Department of Occupational Medicine,the No.12 People′s Hospital of Guangzhou City Affiliated to Guangzhou Medical University, Guangdong Province, Guangzhou 510000,China
AbstractObjective To observe the clinical effect of whole-lung lavage (WLL) in the treatment of pneumoconiosis.Methods A total of 64 pneumoconiosis patients underwent WLL from January 2016 to April 2019 in our hospital were included. The symptom scores as well as the values of partial pressure of oxygen (PaO2), partial pressure of carbon dioxide (PaCO2), maximal ventilatory volume (MVV), forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were appraised. Results After 7 d of lavage, the symptom scores of cough, expectoration and limitation of motion were (0.98±0.10), (1.05±0.11) and (1.02±0.10) points, which were lower than those before lavage ([2.05±0.18],[2.61±0.34], [2.10±0.19]points), the differences were statistically significant (P＜0.05). The value of PaO2 after 7 d of lavage was (12.37±1.13) kPa, which was higher than that before lavage ([9.49±1.25]kPa) (P＜0.05). The value of PaCO2 after 7 d of lavage was (4.68±0.20) kPa, which was lower than that before lavage ([5.19±0.40]kPa) (P＜0.05). The MVV([86.10±1.10]L), FVC ([2.99±0.16]L) and FEV1 ([2.89±0.06]L) were higher than those before lavage ([79.69±1.20),[2.80±0.10]and [2.67±0.10]L) (P＜0.05). Conclusion WLL is proven to be effective, which can improve patients′symptoms, pulmonary function and blood gas indicators.
Shen CH，Chen HJ，Lin TY，et al.Association between pneumoconiosis and pulmonary emboli.a nationwide population-based study in Taiwan[J].Thromb Haemost，2015，113（5）：952-957.
Cho Y，Choi M，Myong JP，et al.The association between bronchial anthracofibrosis and pneumoconiosis： A retrospective cross-sectional study[J].J Occup Health，2015，57（2）：110-117.
