大容量全肺灌洗治疗肺尘埃沉着病的临床效果

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Abstract Objective To observe the clinical effect of whole-lung lavage (WLL) in the treatment of pneumoconiosis.Methods A total of 64 pneumoconiosis patients underwent WLL from January 2016 to April 2019 in our hospital were included. The symptom scores as well as the values of partial pressure of oxygen (PaO2), partial pressure of carbon dioxide (PaCO2), maximal ventilatory volume (MVV), forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were appraised. Results After 7 d of lavage, the symptom scores of cough, expectoration and limitation of motion were (0.98±0.10), (1.05±0.11) and (1.02±0.10) points, which were lower than those before lavage ([2.05±0.18],[2.61±0.34], [2.10±0.19]points), the differences were statistically significant (P＜0.05). The value of PaO2 after 7 d of lavage was (12.37±1.13) kPa, which was higher than that before lavage ([9.49±1.25]kPa) (P＜0.05). The value of PaCO2 after 7 d of lavage was (4.68±0.20) kPa, which was lower than that before lavage ([5.19±0.40]kPa) (P＜0.05). The MVV([86.10±1.10]L), FVC ([2.99±0.16]L) and FEV1 ([2.89±0.06]L) were higher than those before lavage ([79.69±1.20),[2.80±0.10]and [2.67±0.10]L) (P＜0.05). Conclusion WLL is proven to be effective, which can improve patients′symptoms, pulmonary function and blood gas indicators.

Key words： Whole-lung lavage Pneumoconiosis Curative effect Pulmonary function Symptom

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	Articles by authors
	MAI Zi-jian
	YUAN Li-ling
	LIU Yang

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MAI Zi-jian,YUAN Li-ling,LIU Yang. Clinical effect of whole-lung lavage in the treatment of pneumoconiosis[J]. 中国当代医药, 2020, 27(16): 44-46.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I16/44

[1]	朱佑明，甘易玲，夏薇，等.大容量全肺灌洗术对尘肺病合并慢性阻塞性肺疾病的疗效分析[J].临床和实验医学杂志，2017，16（23）：2326-2329.
[2]	刘志光，谭建龙，吴怀球，等.经支气管镜大容量肺灌洗治疗尘肺病合并慢性阻塞性肺疾病的疗效分析[J].中国内镜杂志，2018，24（12）：26-32.
[3]	杨怀宇，石江涛.布地奈德联合复方异丙托溴铵雾化吸入对尘肺病大容量全肺灌洗围术期患者的疗效影响[J].中国药房，2017，28（5）：656-659.
[4]	刘涛，刘红英，赵月鹏，等.尘肺病的综合预防与治疗探讨[J].临床医学研究与实践，2017，2（1）：94-95.
[5]	安金英，陈刚，袁扬，等.双肺同期大容量肺灌洗术治疗尘肺病肺功能评价[J].职业与健康，2019，35（9）：1157-1160.
[6]	于斌.支气管肺灌洗术治疗尘肺的并发症及防治体会[J].中国现代药物应用，2016，10（20）：59-60.
[7]	李堃，任早亮，李家松，等.支气管肺泡灌洗技术治疗尘肺的临床研究[J].中国临床研究，2017，30（2）：200-202.
[8]	张宜强.雾化吸入氨溴索联合支气管镜下肺灌洗治疗尘肺的效果观察[J].国际医药卫生导报，2017，23（16）：2580-2582.
[9]	伍永升，宋利明，王正煜，等.不同容量肺灌洗术对合并慢性阻塞性肺疾病的尘肺病患者血清炎性因子、肺功能和生活质量的影响[J].实用医院临床杂志，2019，16（2）：15-18.
[10]	Shen CH，Chen HJ，Lin TY，et al.Association between pneumoconiosis and pulmonary emboli.a nationwide population-based study in Taiwan[J].Thromb Haemost，2015，113（5）：952-957.
[11]	郭俊华，杨诚，杜焰家，等.大容量全肺灌洗术治疗肺泡蛋白沉积症三例分析[J].国际呼吸杂志，2019，39（3）：225-229.
[12]	张洪文，李艳军，门泽锴，等.尘肺合并慢性阻塞性肺疾病患者的肺灌洗治疗体会[J].中国疗养医学，2018，27（1）：52-54.
[13]	杨华敏.纤维支气管镜肺泡灌洗术治疗尘肺患者的操作及护理[J].临床医药文献电子杂志，2018，5（14）：81-82.
[14]	Cho Y，Choi M，Myong JP，et al.The association between bronchial anthracofibrosis and pneumoconiosis： A retrospective cross-sectional study[J].J Occup Health，2015，57（2）：110-117.
[15]	何钦，朱若凯，容开萍，等.肺泡灌洗术辅助常规药物治疗尘肺临床观察[J].江西医药，2018，53（7）：714-715，718.
[16]	任朝凤，吴涛，杨丽芬，等.大容量全肺灌洗治疗尘肺的疗效观察[J].昆明医科大学学报，2014，35（2）：130-131.