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Clinical effect of Ferrous Lactate Syrup in the treatment of children with iron deficiency anemia |
SUN Wen-jun WANG Yong-hui |
Department of Pediatrics, Dunhuang Hospital, Gansu Province, Dunhuang 736200, China |
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Abstract Objective To observe the clinical effect of Ferrous Lactate Syrup in the treatment of iron deficiency anemia(IDA) in children. Methods A total of 76 children with IDA treated in our hospital from January 2018 to March 2019 were divided into two groups by the random number table method, 38 cases in each group.The control group received Ferrous Succinate Tablets, the observation group received Ferrous Lactate Syrup treatment.The clinical efficacy, parameters of peripheral red blood cells (hemoglobin [Hb], mean corpuscular volume [MCV]), iron metabolism indexes(serum ferritin [SF], serum iron [SI]), total incidence of adverse reactions and recurrence rate were compared between the two groups. Results The total effective rate of the observation group (92.10%) was higher than that of the control group (73.68%), the recurrence rate (5.26%) was lower than that of the control group (21.05%), the differences were statistically significant (P<0.05).There were no significant differences in the levels of Hb, SF, MCV and Si between the two groups before treatment (P>0.05).After treatment, the Hb in observation group was (119.69±6.28) g/L, SF was(38.97±4.08) μg/L, MCV was (90.36±8.35) fl and Si was (15.16±2.38) μmol/L, higher than the control group of (102.64±5.49) g/L, (30.75±3.51) μg/L, (73.84±8.72) fl, (10.94±3.81) μmol/L, the differences were statistically significant (P<0.05).There was no significant difference in the total incidence of adverse reactions between the observation group and control group (5.26% vs.10.53%) (P>0.05). Conclusion Ferrous Lactate Syrup treatment is safe and feasible for IDA children, which is beneficial to improving the level of Hb, SF, MCV, Si, correcting anemia symptoms, and has a low recurrence rate.
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